CRBN ligand-871
CRBN ligand-871 is an E3 ubiquitin ligase cereblon (CRBN) ligand used to recruit the cereblon protein. CRBN ligand-871 can be linked to a target protein ligand via a linker to form a PROTAC.
For research use only. We do not sell to patients.
- Formula: C24H31FN4O5S2
- Molecular Weight:538.66
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
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Cereblon |
PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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Molecular Weight 538.66
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Formula C24H31FN4O5S2
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SMILES
O=S([C@H]1CN(C([C@@H](NC(C)=O)C(C)(C)C)=O)[C@H](C(NCC2=CC=C(C3=C(C)N=CS3)C=C2)=O)C1)(F)=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)