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Cat. No.: HY-162784

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CYP51-IN-19

CYP51-IN-19 (compound C07) is a potent CYP51 inhibitor. CYP51-IN-19 stimulates reactive oxygen species (ROS) and exhibits potent fungicidal activity.

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CAS No.: 3006888-90-7
Formule: C₂₅H₂₇Cl₂N₃O₂
Masse moléculaire:472.41

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Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (268 KB)

CYP51-IN-19 Chemical Structure

CAS No.: 3006888-90-7

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Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Activité biologique
- Description
- Cellular Effect
Chemical Information
Pureté et documentation
Références
Calculators
Help & FAQs
Classifications
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Activité biologique

Description

CYP51-IN-19 (compound C07) is a potent CYP51 inhibitor. CYP51-IN-19 stimulates reactive oxygen species (ROS) and exhibits potent fungicidal activity^[1].

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Cellular Effect

Cell Line	Type	Value	Description	References
J774.A1	IC₅₀	29.37 μM Compound: C07	Cytotoxicity against mouse J774.A1 cells assessed as inhibition of cell growth incubated for 72 hrs by MTT assay Cytotoxicity against mouse J774.A1 cells assessed as inhibition of cell growth incubated for 72 hrs by MTT assay	[PMID: 39077891]

Chemical Information

CAS No. 3006888-90-7
Masse moléculaire 472.41
Formule C₂₅H₂₇Cl₂N₃O₂
SMILES

O=C(NCCCC)/C=C/C1=CC=C(COC(CN2C=CN=C2)C3=CC=C(Cl)C=C3Cl)C=C1
Livraison

Room temperature in continental US; may vary elsewhere.
Stockage

Please store the product under the recommended conditions in the Certificate of Analysis.

Pureté et documentation

Select Batch:

Pureté: 99.98%

Assay: 99.98%

ee.: 99.98%

Fiche technique (268 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Instruction de manipulation (2659 KB)

Références

[1]. Yan Z, et al. Discovery of Novel α,β-Unsaturated Amide Derivatives as Candidate Antifungals to Overcome Fungal Resistance. J Med Chem. 2024 Aug 8;67(15):12601-12617. [Content Brief]

Calculators

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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Activité biologique
- Description
Chemical Information
Pureté et documentation
Références

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CYP51-IN-19

Voir tous les produits spécifiques à Isoform Cytochrome P450