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Cat. No.: HY-117767

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CZ830

CZ830 is a mTOR kinase inhibitor with an IC₅₀ of < 1 μM. CZ830 is applicable to the research of collagen-induced arthritis.

For research use only. We do not sell to patients.

CAS No.: 1333108-58-9
Formula: C₂₅H₂₆F₃N₅O₄S
Molecular Weight:549.57

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

CZ830 Chemical Structure

CAS No.: 1333108-58-9

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Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- Description
- In Vitro
Chemical Information
Purity & Documentation
References
Calculators
Help & FAQs
Bioz

Biological Activity

Description

CZ830 is a mTOR kinase inhibitor with an IC₅₀ of < 1 μM. CZ830 is applicable to the research of collagen-induced arthritis^[1].

All mTOR Isoforms :

In Vitro

CZ830 inhibits mTOR kinase activity with an IC₅₀ of <1 μM, forming specific hydrogen bonds with key mTOR residues Asp2195, Asp2357, and Val2240^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

CAS No. 1333108-58-9
Molecular Weight 549.57
Formula C₂₅H₂₆F₃N₅O₄S
SMILES

S(C)(=O)(=O)C1=C(C2=NC(=NC(=C2)C3=CC=C(NC(NCC(F)F)=O)C=C3)N4[C@@H](C)COCC4)C=C(F)C=C1
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Handling Instructions (2659 KB)

References

[1]. Xu T, et al. Targeting mTOR for fighting diseases: A revisited review of mTOR inhibitors. Eur J Med Chem. 2020;199:112391. [Content Brief]

Calculators

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Keywords

100 mg

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