BMS-981164
Based on 1 Customer Validation
BMS-981164 is a human anti-IL31 IgG1-κ monoclonal antibody. BMS-981164 effectively inhibits the IL-31 signaling pathway. The isotype control of BMS-981164 can be referenced to Human IgG1 kappa, Isotype Control (HY-P99001). BMS-981164 is applicable to research related to atopic dermatitis.
For research use only. We do not sell to patients.
- Purity : 98.69%
- Molecular Weight:146.43 kDa
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Storage:Shipping with dry ice
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
- Protocols
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
Description
Isotype
Human IgG1 kappa
Recommend Isotype Controls
Species Reactivity
Human
IC50 & Target
IL-31
In Vitro
BMS-981164 (0.01-10000 pM; 6 h) inhibits the IL-31 signaling pathway in a dose-dependent manner in PathHunter U2OS IL31RA/OSMR dimerization cells[1].
BMS-981164 (5 nM; 24 h) inhibits IL-4/IL-31-induced CCL2 secretion in human bronchial epithelial BEAS-2B cells[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
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Cell Line:human bronchial epithelial BEAS-2B cells
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Concentration:5 nM
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Incubation Time:24 h
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Result:Inhibited IL-4/IL-31-induced CCL2 secretion in BEAS-2B cells, with efficacy matched by NM26-2198.
Gene ID
Accession
Conjugated
Unconjugated
Reconsititution
The product can be reconstituted/diluted with sterile PBS or saline.
Application
ELISA, FACS, Functional assay
Chemical Information
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Appearance Liquid
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Molecular Weight 146.43 kDa
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Color Colorless to light yellow
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SMILES
[BMS-981164]
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Shipping
Shipping with dry ice.
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Formulation
Please refer to the lot-specific COA for specific buffer information.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
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Data Sheet (258 KB)
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SDS (251 KB)
- English - EN (251 KB)
- Français - FR (251 KB)
- Deutsch - DE (251 KB)
- Norwegian - NO (251 KB)
- Español - ES (251 KB)
- Swedish - SV (251 KB)
- Italian - IT (251 KB)
- Korean - KR (251 KB)
- Portuguese - PT (251 KB)
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Inhibitory Antibodies User Guide (603 KB)
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
BMS-981164 Related Classifications
HY-P991280 Related Classifications
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