CDK9-IN-35
CDK9-IN-35 (compound 10j) is an inhibitor of CDK9/Cyclin T1 with an IC50 value of 10.2 nM and against the HCT-116 cell line with an IC50 value of 20 nM.
For research use only. We do not sell to patients.
- Formula: C26H24ClFN4O4S
- Molecular Weight:543.01
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
Description
Chemical Information
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Molecular Weight 543.01
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Formula C26H24ClFN4O4S
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SMILES
COC1=C(N=C(N=C1)NC2=CC=C(C(Cl)=C2)OCC3=CC=CC(F)=C3)NCC4=CC=C(C=C4)S(C)(=O)=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Protocols
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Cell Cytotoxicity Assay
Cytotoxicity assays are usually based on the assessment of cell membrane damage, which can also be indirectly detected by measuring cell viability. Detection methods include MTT assay, CKK-8 assay, LDH assay and ATP assay, etc.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)