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Epacmarstobart

(Synonyms: FSI-189; GS-0189)
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Epacmarstobart (FSI-189; GS-0189) is an anti-SIRPα humanized antibody that blocks the CD47-SIRPα interaction. Epacmarstobart binds to human SIRPαV1 and SIRPαV2 with Kd values of 4.3 nM and 332 nM, respectively. Epacmarstobart enhances tumor cell phagocytosis in vitro in a SIRPα variant-dependent manner. Epacmarstobart can be used for research on non-Hodgkin lymphoma.

For research use only. We do not sell to patients.

  • Purity : 99.33%
  • CAS No.: 2518200-89-8
  • Molecular Weight:144.94 kDa
  • Storage:
    Shipping with dry ice

    Please store the product under the recommended conditions in the Certificate of Analysis.

  • Experimental Validation Results for Epacmarstobart
  • Experimental Validation Results for Epacmarstobart
  • Epacmarstobart Chemical Structure
    Epacmarstobart Chemical Structure
CAS No.: 2518200-89-8
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To place orders, for customer services and technical support, please contact: MedChemExpress USA

Tel: 609-228-6898 E-mail: [email protected] [email protected]

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Epacmarstobart Product Recommendations:

To place orders, for customer services and technical support, please contact:

609-228-6898
[email protected] [email protected]
Find Your Local Distributor Your local distributor: Hycultec GmbHHycultec
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Assay Types
  • 1/16

    Human IgG1 kappa

  • 1/16

    Flow Cytometry analysis of THP-1 cells labelling SIRPa (red) with Epacmarstobart (anti-SIRPa) (HY-P990019). Cells were stained with the primary antibody at 1/200 dilution for an hour at 4℃. Goat Anti-Human IgG H&L (AF488) (HY-P83776) was used as the secondary antibody at 1/1,000 dilution for 30 minutes at 4℃. Human IgG1 kappa (HY-P99991, blue) was used as the isotype control.

  • Epacmarstobart Chemical Structure
    1/16
  • Epacmarstobart
  • Flow Cytometry analysis of THP-1 cells labelling SIRPa (red) with Epacmarstobart (anti-SIRPa) (HY-P990019). Cells were stained with the primary antibody at 1/200 dilution for an hour at 4℃. Goat Anti-Human IgG H&L (AF488) (HY-P83776) was used as the secondary antibody at 1/1,000 dilution for 30 minutes at 4℃. Human IgG1 kappa (HY-P99991, blue) was used as the isotype control.