JMI-105
JMI-105 is a potent PfFP-2 (Plasmodium falciparum falcipain-2 protease) inhibitor. JMI-105 inhibits the growth of CQS (3D7; IC50=8.8 µM) and CQR (RKL-9; IC50=14.3 µM) strains of P. falciparum. JMI-105 significantly decreases parasitemia and prolonged host survival in a murine model with P. berghei ANKA infection. JMI-105 has the potential to be used as an anti-malarial agent.
For research use only. We do not sell to patients.
- CAS No.: 2227315-30-0
- Formula: C20H23N3O2
- Molecular Weight:337.42
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
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Biological Activity
Chemical Information
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CAS No. 2227315-30-0
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Molecular Weight 337.42
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Formula C20H23N3O2
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SMILES
CC(C1=CC=C(C)C(OCC2=CN(C3=CC=C(OC)C=C3)N=N2)=C1)C
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
JMI-105 Related Classifications
HY-147849 Related Classifications
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