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Cat. No.: HY-N10204

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Rostratin B

Rostratin B, a cytotoxic disulfide, shows in vitro cytotoxicity against human colon carcinoma (HCT-116) with IC₅₀ of 1.9 μg/mL.

For research use only. We do not sell to patients.

CAS No.: 752236-17-2
Formula: C₁₈H₂₀N₂O₆S₂
Molecular Weight:424.49

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (274 KB)

Rostratin B Chemical Structure

CAS No.: 752236-17-2

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Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- Description
- Cellular Effect
Chemical Information
Purity & Documentation
References
Calculators
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Classifications
Bioz

Biological Activity

Description

Rostratin B, a cytotoxic disulfide, shows in vitro cytotoxicity against human colon carcinoma (HCT-116) with IC₅₀ of 1.9 μg/mL^[1].

All Endogenous Metabolite Isoforms :

Cellular Effect

Cell Line	Type	Value	Description	References
HCT-116	IC₅₀	4.4 μM Compound: 2	Cytotoxicity against human HCT116 cells Cytotoxicity against human HCT116 cells	[PMID: 15332857]

Chemical Information

CAS No. 752236-17-2
Molecular Weight 424.49
Formula C₁₈H₂₀N₂O₆S₂
SMILES

O=C(N1[C@]([C@H](CC2)O)([H])[C@](C2=O)([H])C3)[C@@]4(SS[C@]13C5=O)N5[C@]([C@H](CC6)O)([H])[C@](C6=O)([H])C4
Structure Classification
- Alkaloids
- Pyrrole Alkaloids
Initial Source
- Microorganisms
Exserohilum rostratum
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

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Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (274 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Tan RX, et al. Isolation and structure assignments of rostratins A-D, cytotoxic disulfides produced by the marine-derived fungus Exserohilum rostratum. J Nat Prod. 2004;67(8):1374-1382. [Content Brief]

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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Rostratin B

All Endogenous Metabolite Isoforms

Biological Activity

Chemical Information

Purity & Documentation

References

Calculators

Help & FAQs

Rostratin B Related Classifications

HY-N10204 Related Classifications