1. Metabolic Enzyme/Protease
  2. Drug Metabolite
  3. Desmethyl Erlotinib

Desmethyl Erlotinib (Synonyms: OSI-420 free base; CP-373420)

Cat. No.: HY-13256A
Handling Instructions

Desmethyl Erlotinib (OSI-420 free base) is an active metabolite of Erlotinib. Erlotinib is a potent EGFR tyrosin kinase inhibitor.

For research use only. We do not sell to patients.

Desmethyl Erlotinib Chemical Structure

Desmethyl Erlotinib Chemical Structure

CAS No. : 183321-86-0

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Description

Desmethyl Erlotinib (OSI-420 free base) is an active metabolite of Erlotinib. Erlotinib is a potent EGFR tyrosin kinase inhibitor[1].

In Vivo

Desmethyl Erlotinib exhibits t1/2 of 11.96±2.01 h in a pharmacokinetic study in Wistar rats[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

379.41

Formula

C₂₁H₂₁N₃O₄

CAS No.

183321-86-0

SMILES

OCCOC1=CC2=C(N=CN=C2NC3=CC=CC(C#C)=C3)C=C1OCCOC

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Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

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Keywords:

Desmethyl ErlotinibOSI-420 CP-373420OSI420OSI 420CP373420CP 373420CP-373420Drug MetaboliteInhibitorinhibitorinhibit

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Desmethyl Erlotinib
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