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Cat. No.: HY-W747879

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Diclofenac Amide-¹³C₆

Diclofenac Amide-¹³C₆ is the ¹³C-labeled Diclofenac amide (HY-134521). Diclofenac amide is an orally active prodrug of Diclofenac (HY-15036). Diclofenac amide undergoes biotransformation in vivo. Diclofenac amide reduces COX-2 protein expression. Diclofenac amide inhibits Carrageenan (HY-125474)-induced PGE₂ release in peritoneal lavage fluid. Diclofenac amide inhibits Carrageenan-induced paw edema. Diclofenac amide can be used for inflammation research.

For research use only. We do not sell to patients.

Formula: C₈¹³C₆H₉Cl₂NO
Molecular Weight:284.09

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (279 KB)

Diclofenac Amide-¹³C₆ Chemical Structure

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Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- Description
- IC₅₀ & Target
- Application
Chemical Information
Purity & Documentation
References
Calculators
Help & FAQs
Classifications
Bioz

Biological Activity

Description

IC₅₀ & Target

^[1]

COX-2

All COX Isoforms :

Application

1. This compound can be used as a tracer
2. This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.

Chemical Information

Unlabeled CAS 15362-40-0
Molecular Weight 284.09
Formula C₈¹³C₆H₉Cl₂NO
SMILES

O=C1C[13C]2=[13C]([13C]([H])=[13C]([13C]([H])=[13C]2N1C3=C(C=CC=C3Cl)Cl)[H])[H]
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (279 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Santos JL, et al. Pharmacological evaluation and preliminary pharmacokinetics studies of a new diclofenac prodrug without gastric ulceration effect. International journal of molecular sciences. 2012 Nov 19;13(11):15305-20. [Content Brief]

[2]. Monteagudo JM, et al. Sono-activated persulfate oxidation of diclofenac: Degradation, kinetics, pathway and contribution of the different radicals involved. Journal of hazardous materials. 2018 Sep 05;357:457-465.

[3]. Yusuf A O, et al. Photocatalytic degradation of diclofenac amide in a fixed-bed reactor using TiO2/β-Bi2O3: Process optimization and stability analysis[J]. Journal of Photochemistry and Photobiology A: Chemistry, 2024, 450: 115470.

[4]. Yusuf A, et al. Multiphysics computational fluid dynamics (CFD) modelling of diclofenac amide removal by photocatalytic oxidation on Fe-TiO2/N-TiO2 thin films microreactor[J]. Chemical Engineering Science, 2023, 274: 118662.

Calculators

Molarity Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Dilution Calculator

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Bioz

MOQ

Minimum order quantity

100 mg

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Biological Activity
- Description
- IC₅₀ & Target
- Application
Chemical Information
Purity & Documentation
References

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Diclofenac Amide-¹³C₆

All COX Isoforms