Dimethylmalonic acid (Standard)
Dimethylmalonic acid (Standard) (Dimethylpropanedioic acid (Standard)) is the analytical standard of Dimethylmalonic acid (HY-W007894). This product is intended for research and analytical applications. Dimethylmalonic acid (Dimethylpropanedioic acid) is a succinate dehydrogenase inhibitor. Dimethylmalonic acid competitively inhibits succinate dehydrogenase, reduces SDH-mediated succinate accumulation, blocks a key step in oxidative phosphorylation, and decreases anti-inflammatory cytokine secretion and ROS production. Dimethylmalonic acid can be used in research on autism spectrum disorders.
For research use only. We do not sell to patients.
- Purity : 95%
- CAS No.: 595-46-0
- Formula: C5H8O4
- Molecular Weight:132.11
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Product Information
Information
Application
The compound is the grade of analytical standard, which is the reference standard supplied assay. It is commonly used in qualitative, quantitative and methodological research experiments in HPLC, GC and MS.
Chemical Information
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CAS No. 595-46-0
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Molecular Weight 132.11
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Formula C5H8O4
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SMILES
O=C(O)C(C)(C)C(O)=O
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Synonyms
Dimethylpropanedioic acid (Standard)
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Structure Classification
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Initial Source
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Keywords
- Dimethylmalonic acid (Standard)
- 595-46-0
- Dimethylpropanedioic acid (Standard)
- Reference Standards
- Succinate Dehydrogenase
- Reactive Oxygen Species (ROS)
- Oxidative Phosphorylation
- neuronal ferroptosis signaling pathways
- ROS production
- oxidative phosphorylation
- anti-inflammatory cytokine secretion
- valproic acid-induced neurodevelopmental impairments
- succinate dehydrogenase inhibitor
- succinate dehydrogenase
- Achromobacter sp. strain
- autism spectrum disorder
- neonatal valproic acid autism model
- Inhibitor
- inhibitor
- inhibit