CDK4-IN-6
CDK4-IN-6 is a CDK4 inhibitor with an IC50 of 0.0011 μM. CDK4-IN-6 can be used for the research of breast cancer.
For research use only. We do not sell to patients.
- CAS No.: 3120500-44-6
- Formula: C20H29FN6O3S
- Molecular Weight:452.55
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
- Protocols
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
Description
IC50 & Target
[1]|
CDK4 0.0011 μM (IC50) |
In Vitro
Chemical Information
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CAS No. 3120500-44-6
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Molecular Weight 452.55
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Formula C20H29FN6O3S
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SMILES
O[C@H](CN(S(=O)(C)=O)CC1)[C@@H]1NC2=NC=C3C(N([C@@H]4CCNC[C@@H]4F)C(C5CC5)=C3)=N2
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Protocols
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Cell Cytotoxicity Assay
Cytotoxicity assays are usually based on the assessment of cell membrane damage, which can also be indirectly detected by measuring cell viability. Detection methods include MTT assay, CKK-8 assay, LDH assay and ATP assay, etc.
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Breast Cancer Modeling
Breast cancer is a heterogeneous cancer, and it has been distinguished into four subtypes: luminal A, luminal B, HER2-positive and basal-like. Molecular mutations, epigenetic alterations, hormone exposure and immune microenvironment are related to the progression of breast cancer.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
CDK4-IN-6 Related Classifications
HY-184418 Related Classifications
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