CDK8-IN-18
CDK8-IN-18 (compound BRD-2299) is a potent inhibitor of CDK8, with the IC50 of 43 μM. CDK8-IN-18 plays an important role in cancer research.
For research use only. We do not sell to patients.
- CAS No.: 642002-74-2
- Formula: C16H18N4
- Molecular Weight:266.34
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
Description
IC50 & Target
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CDK8 43 μM (IC50) |
Chemical Information
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CAS No. 642002-74-2
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Molecular Weight 266.34
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Formula C16H18N4
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SMILES
N#CC1=C(C2=CN=CC=C2)C(CC)=C(CCC)N=C1N
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Protocols
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Cell Cytotoxicity Assay
Cytotoxicity assays are usually based on the assessment of cell membrane damage, which can also be indirectly detected by measuring cell viability. Detection methods include MTT assay, CKK-8 assay, LDH assay and ATP assay, etc.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)