NTRK3 - neurotrophic receptor tyrosine kinase 3 Gene

Also Known as TRKC; GP145-TrkC; gp145(trkC)

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 4916

About NTRK3

Cytogenetic location: 15q25.3 Genomic coordinates (GRCh38): 15:87,859,751-88,256,739 (from NCBI)

This gene has 19 transcripts (splice variants), 271 orthologues, 53 paralogues and is associated with 138 phenotypes. Biased expression in brain (RPKM 2.8), fat (RPKM 1.2) and 13 other tissues.

Summary

This gene encodes a member of the neurotrophic tyrosine receptor kinase (NTRK) family. This kinase is a membrane-bound receptor that, upon neurotrophin binding, phosphorylates itself and members of the MAPK pathway. Signalling through this kinase leads to cell differentiation and may play a role in the development of proprioceptive neurons that sense body position. Mutations in this gene have been associated with medulloblastomas, secretory breast carcinomas and Other cancers. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2011]

NTRK3 Products (34)

mRNA Protein Name
NM_001012338.3 NP_001012338.1 NT-3 growth factor receptor isoform a precursor
XM_017022252.3 XP_016877741.1 NT-3 growth factor receptor isoform X17
XM_024449934.2 XP_024305702.1 NT-3 growth factor receptor isoform X6
NM_001375811.1 NP_001362740.1 NT-3 growth factor receptor isoform b precursor
XM_017022245.3 XP_016877734.1 NT-3 growth factor receptor isoform X4
NM_001320134.1 NP_001307063.1 NT-3 growth factor receptor isoform e precursor
XM_017022251.3 XP_016877740.1 NT-3 growth factor receptor isoform X16
NM_001320135.2 NP_001307064.1 NT-3 growth factor receptor isoform f
XM_017022254.3 XP_016877743.1 NT-3 growth factor receptor isoform X18
XM_017022241.2 XP_016877730.1 NT-3 growth factor receptor isoform X2
XM_017022240.2 XP_016877729.1 NT-3 growth factor receptor isoform X1
XM_006720549.5 XP_006720612.1 NT-3 growth factor receptor isoform X11
XR_002957645.2
XM_017022242.3 XP_016877731.1 NT-3 growth factor receptor isoform X3
NM_001375812.1 NP_001362741.1 NT-3 growth factor receptor isoform d precursor
XM_047432602.1 XP_047288558.1 NT-3 growth factor receptor isoform X7
XR_001751292.3
XM_024449935.2 XP_024305703.1 NT-3 growth factor receptor isoform X9
NM_001243101.2 NP_001230030.1 NT-3 growth factor receptor isoform d precursor
XM_017022250.3 XP_016877739.1 NT-3 growth factor receptor isoform X13
NM_001375813.1 NP_001362742.1 NT-3 growth factor receptor isoform c precursor
XM_006720545.5 XP_006720608.1 NT-3 growth factor receptor isoform X5
NM_001007156.3 NP_001007157.1 NT-3 growth factor receptor isoform c precursor
XM_006720550.5 XP_006720613.1 NT-3 growth factor receptor isoform X12
XM_011521638.4 XP_011519940.1 NT-3 growth factor receptor isoform X14
NM_002530.4 NP_002521.2 NT-3 growth factor receptor isoform b precursor
XM_047432604.1 XP_047288560.1 NT-3 growth factor receptor isoform X15
XR_001751293.3
NM_001375814.1 NP_001362743.1 NT-3 growth factor receptor isoform g precursor
XM_017022244.3 XP_016877733.1 NT-3 growth factor receptor isoform X4
XM_006720548.5 XP_006720611.1 NT-3 growth factor receptor isoform X10
XM_047432603.1 XP_047288559.1 NT-3 growth factor receptor isoform X8
NM_001375810.1 NP_001362739.1 NT-3 growth factor receptor isoform a precursor
XM_017022243.2 XP_016877732.1 NT-3 growth factor receptor isoform X4

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables neurotrophin receptor activity IDA
IDA: Inferred from direct assay
23027130 GOA
enables p53 binding IPI
IPI: Inferred from physical interaction
23027130 GOA
enables protein binding IPI
IPI: Inferred from physical interaction
12237455 GOA
Biological Process GO Annotation Evidence References Source
involved in activation of GTPase activity IDA
IDA: Inferred from direct assay
23027130 GOA
acts upstream of activation of protein kinase B activity IDA
IDA: Inferred from direct assay
23027130 GOA
involved in cell surface receptor protein tyrosine kinase signaling pathway IDA
IDA: Inferred from direct assay
23027130 GOA
involved in heart development IMP
IMP: Inferred from mutant phenotype
25196463 GOA
involved in negative regulation of protein phosphorylation IDA
IDA: Inferred from direct assay
23027130 GOA
acts upstream of positive regulation of MAP kinase activity IDA
IDA: Inferred from direct assay
23027130 GOA
involved in positive regulation of cell migration IDA
IDA: Inferred from direct assay
23027130 GOA
involved in positive regulation of cell population proliferation IDA
IDA: Inferred from direct assay
23027130 GOA
involved in positive regulation of gene expression IDA
IDA: Inferred from direct assay
23027130 GOA
involved in positive regulation of peptidyl-serine phosphorylation IDA
IDA: Inferred from direct assay
23027130 GOA
involved in positive regulation of positive chemotaxis IDA
IDA: Inferred from direct assay
23027130 GOA
Cellular Component GO Annotation Evidence References Source
part of receptor complex IDA
IDA: Inferred from direct assay
23382219 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

NTRK3 Protein Structure

LRRNT

LRRNT: Leucine rich repeat N-terminal domain (31 - 56)

LRR_8

LRR_8: Leucine rich repeat (104 - 160)

I-set

I-set: Immunoglobulin I-set domain (210 - 301)

I-set

I-set: Immunoglobulin I-set domain (323 - 391)

Pkinase_Tyr

Pkinase_Tyr: Protein tyrosine kinase (539 - 824)

  • 0
  • 200
  • 400
  • 600
  • 800
  • 839 a.a.
Protein Preferred Names Protein Names

NT-3 growth factor receptor

  • ETS related protein-neurotrophic receptor tyrosine kinase fusion protein

  • ETV6-NTRK3 fusion

  • neurotrophic tyrosine kinase, receptor, type 3

  • tyrosine kinase receptor C

NTRK3 Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method References
Intra
NTRK3 Q16288 NTRK1 Homo sapiens P04629
Affinity Chrom
35384245
Intra
NTRK3 Q16288 MET Homo sapiens P08581
Affinity Chrom
35384245
Intra
NTRK3 Q16288 MET Homo sapiens P08581
Anti Tag CoIP
35384245
Intra
NTRK3 Q16288 SORT1 Homo sapiens Q99523
Anti Bait CoIP
21102451
Intra
NTRK3 Q16288 YWHAE Homo sapiens P62258
Crosslink
36931259
Intra
NTRK3 Q16288 SEL1L Homo sapiens Q9UBV2
Anti Tag CoIP
35384245
Intra
NTRK3 Q16288 SEL1L Homo sapiens Q9UBV2
Affinity Chrom
35384245
Intra
NTRK3 Q16288 SEC61A1 Homo sapiens P61619
Affinity Chrom
35384245
Intra
NTRK3 Q16288 SEC61A1 Homo sapiens P61619
Anti Tag CoIP
35384245
Intra
NTRK3 Q16288 NTRK2 Homo sapiens Q16620
BioID
35384245
Intra
NTRK3 Q16288 NTRK2 Homo sapiens Q16620
Affinity Chrom
35384245
Intra
NTRK3 Q16288 SFN Homo sapiens P31947
Pull Down
32707033
Intra
NTRK3 Q16288 PTPN1 Homo sapiens P18031
BioID
35384245
Cross: Cross-species interaction Intra: Intraspecies interaction

Recombinant NTRK3 Proteins

Cat. No. Product Name Accession Purity
HY-P73464 TrkC Protein, Human (HEK293, His-Fc) Q16288-2/NP_001007157.1 (C32-D428) ≥ 95%, as determined by reducing SDS-PAGE.
HY-P73465 TrkC Protein, Human (HEK293, His) Q16288-2/NP_001007157.1 (C32-D428) ≥ 95%, as determined by reducing SDS-PAGE.

NTRK3 Antibodies

Cat. No. Product Name Application Reactivity
HY-P84610 Trk C Antibody (YA4307) WB, IHC-P, ELISA Human
HY-P84610A Trk C Antibody (YA4307)(PBS only) WB, IHC-P, ELISA Human
HY-P85397 Trk C Antibody (YA5089) WB Human, Mouse, Rat
HY-P86247 Trk pan Antibody (YA5939) WB, ICC/IF, IP, ELISA Human, Mouse, Rat

Related Diseases

Diseases Alias
Kidney Rhabdoid Cancer

  • Rhabdoid Tumor Of The Kidney

  • Kidney Rhabdoid Tumor

  • Renal Rhabdoid Tumor
Spindle Cell Sarcoma

  • Sarcoma

  • Sarcoma Spindle Cell

  • Sarcoma, Spindle Cell

  • Sarcoma - Category
Tonsil Cancer

  • Tonsillar Neoplasms

  • Malignant Neoplasm Of Faucial Tonsil

  • Malignant Neoplasm Of Palatine Tonsil

  • Malignant Neoplasm Of Tonsil, Faucial

  • Malignant Tonsillar Tumor

  • Malignant Tumor Of Tonsil

  • Tonsillar Carcinoma

  • Malignant Neoplasm Tonsil
Salivary Gland Adenoid Cystic Carcinoma

  • Cylindroma
Gastrointestinal Stromal Tumor

  • GIST

  • Gastrointestinal Stromal Tumors

  • Gastrointestinal Stromal Sarcoma

  • Gastrointestinal Stromal Tumor, Familial

  • Gant

  • Gastrointestinal Stromal Tumour

  • Stromal Tumor Of Gastrointestinal Tract

  • Stromal Tumour Of Gastrointestinal Tract

  • Gastrointestinal Stromal Neoplasm

  • Paraganglioma And Gastric Stromal Sarcoma

  • Plexosarcoma
Childhood Fibrosarcoma

  • Pediatric Fibrosarcoma
Cellular Congenital Mesoblastic Nephroma
Glioma
Mastocytosis

  • Mast Cell Disease

  • Mast Cell Hyperplasia

  • Urticaria Pigmentosa

  • Malignant Mastocytoma

  • Malignant Mast Cell Tumours

  • Malignant Mastocytosis
Spitzoid Melanoma

  • Atypical Spitz Nevus
Mast-Cell Leukemia

  • Mast Cell Leukemia

  • Leukemia, Mast-Cell

  • Leukemia Mast Cell

  • Mast Cell Leukaemia Nos

  • Mast Cell Leukaemia Without Mention Of Remission
Tetralogy Of Fallot

  • TOF

  • Fallot Tetralogy

  • Ventricular Septal Defect With Pulmonary Stenosis Or Atresia, Dextraposition Of Aorta, And Hypertrophy Of Right Ventricle

  • Tetrad Of Fallot

  • Fallot Tetrad

  • Fallot Disease

  • Fallot Complex

  • Subpulmonic Stenosis, Ventricular Septal Defect, Overriding Aorta, And Right Ventricular Hypertrophy

  • Interventricular Septal Defect With Dextroposition Of Aorta, Pulmonary Stenosis And Hypertrophy Of Right Ventricle

  • Interventricular Septal Defect, In Tetralogy Of Fallot

  • Ventricular Septal Defect With Obstructed Right Ventricular Outflow

  • Tof - [Tetralogy Of Fallot]

  • Pulmonary Atresia With Ventricular Septal Defect [Fallot Type]

  • Pulmonary Atresia, Ventricular Septal Defect And Mapcas

  • Pulmonary Atresia With Ventricular Septal Defect And Systemic-To-Pulmonary Collateral Arteries [Fallot Type]
Hirschsprung Disease 1

  • Hirschsprung Disease

  • Aganglionic Megacolon

  • Hscr

  • Congenital Megacolon

  • Colonic Aganglionosis

  • Hirschsprung Disease, Susceptibility To, 1

  • Hirschsprung Disease, Protection Against

  • Hirschsprung'S Disease

  • Congenital Intestinal Aganglionosis

  • HSCR1

  • Mgc

  • Pelvirectal Achalasia

  • Total Intestinal Aganglionosis

  • Megacolon, Aganglionic

  • Macrocolon

  • Hscr 1

  • Hirschsprung Disease Type 1

  • Hirschsprung Disease, Type 1

  • Congenital Dilatation Of Colon

  • Aganglionosis

  • Congenital Aganglionic Megacolon

  • Aganglionosis Of Colon

  • Bowel Aganglionosis

  • Colon Aganglionosis

  • Hirschsprung Megacolon
Lipid-Rich Carcinoma
Pregnancy Adenoma

  • Lactating Adenoma
Acinar Cell Carcinoma

  • Acinic Cell Carcinoma

  • Acinic Cell Tumor

  • Carcinoma Acinar Cell

  • Carcinoma, Acinar Cell

  • Acinar Cell Tumor
Congenital Mesoblastic Nephroma

  • Nephroma, Mesoblastic

  • Mesoblastic Nephroma
Schizophrenia

  • SCZD

  • Schizophrenia With Or Without An Affective Disorder

  • Schizophrenia 12

  • Schizophrenia, Susceptibility To

  • Schizophrenia-1

  • Dementia Praecox

  • Schizophrenia 1
Ganglioneuroma
Mixed Lacrimal Gland Cancer

  • Carcinoma Ex Pleomorphic Adenoma Of Lacrimal Gland

  • Carcinoma Ex Pleomorphic Adenoma Of The Lacrimal Gland

  • Malignant Mixed Neoplasm Of Lacrimal Gland
Breast Secretory Carcinoma

  • Secretory Breast Carcinoma

  • Juvenile Breast Carcinoma

  • Juvenile Carcinoma Of The Breast

  • Juvenile Secretory Carcinoma Of Breast

  • Juvenile Breast Cancer

  • Sbc

  • Secretory Carcinoma Of The Breast
Inflammatory Myofibroblastic Tumor

  • Inflammatory Fibrosarcoma
Thyroid Gland Cancer

  • Thyroid Gland Carcinoma

  • Malignant Neoplasm Of Thyroid Gland

  • Malignant Tumour Of Thyroid Gland

  • Thyroid Neoplasm

  • Thyroid Neoplasms

  • Neoplasm Of Thyroid Gland

  • Thyroid Gland Neoplasm

  • Head And Neck Cancer, Thyroid

  • Neoplasm Of The Thyroid Gland

  • Cancer Of The Thyroid

  • Primary Malignant Neoplasm Of Thyroglossal Duct

  • Malignant Neoplasm Of Thyroglossal Duct

  • Primary Malignant Neoplasm Of Thyroid Gland

  • Thyroglossal Duct Cancer

  • Toxic Goitre Malignant Tumour

  • Cancerous Goitre
Congenital Fibrosarcoma

  • Infantile Fibrosarcoma
Leukemia, Chronic Myeloid

  • Chronic Myeloid Leukemia

  • Chronic Myelogenous Leukemia

  • CML

  • Chronic Granulocytic Leukemia

  • Leukemia, Philadelphia Chromosome-Positive, Resistant To Imatinib

  • Chronic Myeloid Leukaemia

  • Chronic Granulocytic Leukaemia

  • Chronic Myelogenous Leukaemia

  • Myeloid Leukemia, Chronic

  • Leukemia, Chronic Myelogenous

  • Leukemia, Chronic Myeloid, Philadelphia Chromosome Positive, Somatic

  • Cml - Chronic Myelogenous Leukemia

  • Cgl

  • Chronic Myelocytic Leukemia

  • Leukemia, Chronic Myeloid, Atypical

  • ACML

  • Atypical Chronic Myeloid Leukemia Bcr-Abl1 Negative

  • Myeloid Leukemia Chronic

  • Leukemia, Myeloid, Chronic

  • Leukemia, Myeloid, Chronic, Atypical, Bcr-Abl Negative

  • Cml- [Chronic Myeloid Leukaemia]

  • Cgl - [Chronic Granulocytic Leukaemia]

  • Chronic Myelocytic Leukaemia
Panic Disorder

  • Panic Anxiety Syndrome

  • Panic

  • Panic Disorder 1

  • Episodic Paroxysmal Anxiety Disorder
Breast Cancer

  • Breast Carcinoma

  • Breast Cancer, Familial

  • Malignant Neoplasm Of Breast

  • Male Breast Cancer

  • Breast Cancer, Susceptibility To

  • Breast Cancer, Early-Onset

  • Malignant Tumor Of Breast

  • Carcinoma Of Male Breast

  • Breast Cancer, Invasive Ductal

  • Breast Cancer, Protection Against

  • Breast Cancer, Somatic

  • Breast Cancer, Male

  • Breast Cancer, Lobular, Somatic

  • Breast Tumor

  • Mammary Cancer

  • Mammary Tumor

  • Malignant Neoplasm Of Male Breast

  • Mammary Carcinoma

  • Male Breast Carcinoma

  • Familial Cancer Of Breast

  • Invasive Ductal Breast Carcinoma

  • Breast Cancer Susceptibility

  • Breast Cancer, Male, Susceptibility To

  • Breast Cancer, Early-Onset, Susceptibility To

  • Malignant Tumor Of The Breast

  • Mammary Neoplasm

  • Primary Breast Cancer

  • Neoplasm Of Male Breast

  • Carcinoma Of Breast

  • Breast Cancer In Men

  • Familial Breast Cancer

  • Cancer Of Breast

  • BC

  • Breast Cancer Familial

  • Breast Cancer Familial Male

  • Breast Cancer, Familial Male

  • Breast Male Carcinoma

  • Breast Neoplasms

  • Breast Neoplasms, Male

  • Mammary Tumors

  • Mammary Carcinomas

  • Cancer, Breast

  • Cancer, Breast, Susceptibility

  • Invasive Breast Ductal Carcinoma

  • Breast Neoplasm

  • Susceptibility To Breast Cancer

  • Mammary Neoplasms

  • Animal Mammary Neoplasms

  • Primary Malignant Neoplasm Of Breast

  • Infiltrating Ductal Carcinoma Of Breast

  • Infiltrating Duct Carcinoma Of Unspecified Site

  • Infiltrating Ductular Carcinoma Of Unspecified Site

  • Invasive Breast Carcinoma Of No Special Type

  • Microinvasive Carcinoma Of Breast

  • Carcinoma With Apocrine Differentiation
Spiradenoma

  • Eccrine Spiradenoma

  • Benign Eccrine Spiradenoma

  • Eccrine Spiradenoma Of Skin

  • Es

  • Eccrine Spiradenoma, Benign
Kidney Fibrosarcoma

  • Fibrosarcoma Of The Kidney
Mammary Analogue Secretory Carcinoma
Mast Cell Neoplasm

  • Mastocytoma

  • Mast Cell Proliferative Disease

  • Mast Cell Tumor

  • Benign Mastocytoma
Constipation
Neuroblastoma

  • Nb

  • Neuroblastoma, Susceptibility To

  • Neuroblastomas

  • Central Neuroblastoma
Kidney Clear Cell Sarcoma

  • Clear Cell Sarcoma Of Kidney

  • Childhood Kidney Clear Cell Sarcoma

  • Renal Clear Cell Sarcoma

  • Ccsk

  • Clear Cell Sarcoma Of The Kidney
Asperger Syndrome

  • Asperger Disorder
Breast Adenoid Cystic Carcinoma

  • Adenoid Cystic Breast Carcinoma

  • Adenoid Cystic Carcinoma Of Breast

  • Mammary Adenocystic Carcinoma
Fibrosarcoma

  • Neoplasms, Fibrous Tissue

  • Fibrocytic Tumor

  • Fibrosarcoma Of Soft Tissue

  • Fibrous Tissue Neoplasm
Parotid Gland Cancer

  • Cancer Of Parotid Gland

  • Parotid Neoplasms

  • Malignant Neoplasm Of The Parotid

  • Malignant Tumor Of Parotid Gland

  • Parotid Cancer

  • Parotid Neoplasm

  • Parotid Gland Carcinoma

  • Cancer Of Parotid

  • Malignant Tumour Of Parotid Gland

  • Parotid Duct Cancer

  • Parotid Ductal Cancer

  • Parotid Glandular Cancer

  • Primary Malignant Neoplasm Of Parotid Gland
Alzheimer Disease, Familial, 1

  • Alzheimer Disease

  • Alzheimer'S Disease

  • Presenile And Senile Dementia

  • AD1

  • Alzheimer Disease, Susceptibility To

  • Alzheimer Disease, Late-Onset, Susceptibility To

  • Alzheimer Disease 1, Familial

  • AD

  • Familial Alzheimer Disease

  • Alzheimer Disease, Late-Onset

  • Alzheimers Dementia

  • Alzheimer Dementia

  • Alzheimer Sclerosis

  • Alzheimer Syndrome

  • Alzheimer-Type Dementia

  • Dat

  • Primary Senile Degenerative Dementia

  • Sdat

  • Alzheimer Disease 1

  • Autosomal Dominant Alzheimer Disease

  • Early-Onset Alzheimer Disease With Cerebral Amyloid Angiopathy

  • Late Onset Alzheimer Disease

  • Alzheimers Disease

  • Alzheimer Disease, Early-Onset, With Cerebral Amyloid Angiopathy

  • Late-Onset Alzheimers Disease

  • Alzheimer'S Disease Pathway Kegg

  • Dementia Due To Alzheimer'S Disease

  • Alzheimer Disease Type 1

  • Alzheimers
Brain Cancer

  • Malignant Neoplasm Of Brain

  • Adult Brain Tumor

  • Brain Neoplasms

  • Brain Neoplasm

  • Neoplasm Of Brain

  • Primary Malignant Neoplasm Of Brain

  • Brain Tumors

  • Adult Malignant Brain Neoplasm

  • Brain Neoplasm, Adult

  • Bt - Brain Tumour

  • Malignant Brain Tumour

  • Malignant Primary Brain Neoplasm

  • Malignant Primary Brain Tumor

  • Malignant Tumor Of Adult Brain

  • Malignant Tumor Of Brain

  • Primary Brain Neoplasm

  • Primary Brain Tumor

  • Tumor Of The Brain

  • Brain Tumor, Adult

  • Brain Tumor Primary

  • Malignant Primary Brain Tumors

  • Primary Brain Tumors

  • Cancer, Brain

  • Brain Tumor, Primary
Nephroma

  • Benign Nephroma
Dermatofibrosarcoma Protuberans

  • DFSP

  • Dermatofibrosarcoma

  • Giant Cell Fibroblastoma

  • Metastatic Dermatofibrosarcoma Protuberans

  • Familial Dermatofibrosarcoma Protuberans

  • Darier-Ferrand Tumor

  • Darier-Hoffmann Tumor
Lipofibromatosis-Like Neural Tumor
Salivary Gland Carcinoma

  • Salivary Gland Cancer

  • Malignant Neoplasm Of Salivary Gland

  • Salivary Gland Neoplasms
Breast Adenocarcinoma

  • Mammary Adenocarcinoma

  • Adenocarcinoma Of Breast
Infantile Myofibromatosis

  • Lipofibromatosis

  • Myofibromatosis
Pleomorphic Adenoma Carcinoma

  • Carcinoma Ex Pleomorphic Adenoma

  • Carcinoma In Pleomorphic Adenoma
Mucoepidermoid Carcinoma

  • Mec

  • Salivary Gland Mucoepidermoid Carcinoma

  • C3772

  • Carcinoma Mucoepidermoid

  • Carcinoma, Mucoepidermoid
Peripheral Nervous System Disease

  • Peripheral Neuropathy

  • Peripheral Nerve Disease

  • Peripheral Nerve Disorders

  • Neuropathy, Peripheral

  • Peripheral Neuropathy Due To Vitamin Pyridoxine Hyperalimentation
Paraganglioma

  • Chemodectoma

  • Glomus Body Tumor

  • Paragangliomas

  • Carotid Body Paraganglioma

  • Extra-Adrenal Paraganglioma
Breast Juvenile Papillomatosis

  • Juvenile Papillomatosis Of The Breast
Thyroid Gland Follicular Carcinoma

  • Follicular Thyroid Carcinoma

  • Follicular Adenocarcinoma

  • Follicular Adenocarcinoma, Well Differentiated

  • Follicular Carcinoma

  • Thyroid Adenocarcinoma

  • Adenocarcinoma, Follicular
Adult Fibrosarcoma
Oligodendroglioma

  • Oligodendroglial Neoplasm

  • Oligodendroglial Tumor

  • Oligodendroglial Tumors

  • Well Differentiated Oligodendroglioma
Malignant Giant Cell Tumor Of The Tendon Sheath

  • Giant Cell Tumour Of Tendon Sheath, Malignant

  • Malignant Giant Cell Neoplasm Of The Tendon Sheath
Differentiated Thyroid Carcinoma

  • Papillary Or Follicular Thyroid Carcinoma

  • Well-Differentiated Thyroid Carcinoma

  • Differentiated Thyroid Gland Carcinoma
Mesenchymal Cell Neoplasm

  • Benign Miscellaneous Mesenchymal Tumor

  • Mesenchymal Tumor

  • Mesenchymal Tumors
Medulloblastoma

  • MDB

  • Cpnet

  • Localized Primitive Neuroectodermal Tumor

  • Classic Medulloblastoma

  • Desmoplastic/Nodular Medulloblastoma

  • Medulloblastoma With Extensive Nodularity

  • Desmoplastic Medulloblastoma

  • Medulloblastoma, Somatic

  • Medulloblastoma, Desmoplastic

  • Brain Medulloblastoma

  • Cns Pnet

  • Infratentorial Primitive Neuroectodermal Tumor

  • Mben

  • Medulloblastoma Desmoplastic

  • Neuroectodermal Tumors, Primitive

  • Medulloblastomas

  • Medulloblastoma, With Extensive Nodularity

  • Medulloblastoma Of Unspecified Site

  • Medullomyoblastoma Of Unspecified Site
Oropharynx Cancer

  • Oropharyngeal Cancer

  • Oropharyngeal Carcinoma

  • Malignant Neoplasm Of Oropharynx

  • Malignant Oropharyngeal Tumor

  • Malignant Tumor Of Oropharynx

  • Malignant Tumour Of Mesopharynx

  • Oropharyngeal Cancer, Adult

  • Cancer Of The Oropharynx
Salivary Gland Disease

  • Salivary Gland Disorders

  • Salivary Gland Diseases

  • Non-Neoplastic Salivary Gland Disease

  • Non-Neoplastic Salivary Gland Disorder

  • Disorder Of Salivary Gland

  • Lesion Of Salivary Gland Nos
Epithelial-Myoepithelial Carcinoma

  • Clear Cell Adenoma

  • Adenomyo-Epithelioma

  • Clear Cell Carcinoma

  • Emc

  • Epithelial Myoepithelial Carcinoma

  • Glycogen-Rich Adenocarcinoma

  • Glycogen-Rich Adenoma

  • Monomorphic Clear Cell Tumor

  • Tubular Solid Adenoma

  • Adenocarcinoma, Clear Cell
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

  • Clinical Phase
  • Pre-clinical Phase

Clinical Phase

Bioactive Molecules (2)
Cat. No. Product Name Effect
Purity Phase
HY-131003A Taletrectinib free base Inhibitor / Phase 3
HY-131003 Taletrectinib Inhibitor 99.63% Phase 2

Pre-clinical Phase

Bioactive Molecules (6)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS09634 NTRK3 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-W070306 PDK1-IN-1 Inhibitor 99.95% Unkown
HY-101977A (R,S)-Selitrectinib Inhibitor / Unkown
HY-115541 BRD4-IN-41 Inhibitor / Unkown
HY-RS09635 Ntrk3 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS09636 Ntrk3 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown
Inhibitory Antibodies (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-P992308 Anti-TrkC Antibody / Unkown

Orthologs Information

Species Symbol Source ID
Macaca mulatta NTRK3 VGNC VGNC:75542
Canis familiaris NTRK3 VGNC VGNC:49932
Bos taurus NTRK3 VGNC VGNC:106849
Felis catus NTRK3 VGNC VGNC:68580
Rattus norvegicus NTRK3 RGD RGD:3214
Mus musculus NTRK3 MGD MGI:97385
Others NTRK3 NCBI