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Movronersen

(Synonyms: BIIB-101; ION-464)

Movronersen (BIIB-101; ION-464) is an antisense oligonucleotide that targets SNCA; it promotes the degradation of SNCA mRNA and downregulates the synthesis of α-synuclein. By reducing the production of α-synuclein, Movronersen decreases protein misfolding and aggregation, thereby interfering with the pathological progression of synucleinopathies. Movronersen is used in research related to multiple system atrophy and associated disorders.

For research use only. We do not sell to patients.

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    Please store the product under the recommended conditions in the Certificate of Analysis.

  • Movronersen Chemical Structure
    Movronersen Chemical Structure
CAS No.: 2411937-33-0
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To place orders, for customer services and technical support, please contact:

609-228-6898
[email protected] [email protected]
Find Your Local Distributor Your local distributor: Hycultec GmbHHycultec
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Top Publications Citing

Use of MCE Products

All α-synuclein Isoforms

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All DNA/RNA Synthesis Isoforms

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  • Movronersen Chemical Structure
    Movronersen Chemical Structure DNA, d([2'-O-(2-methoxyethyl)]rA-sp-[2'-O-(2-methoxyethyl)]m5rC-[2'-O-(2-methoxyethyl)]rA-sp-[2'-O-(2-methoxyethyl)]rG-sp-[2'-O-(2-methoxyethyl)]rA-sp-T-sp-A-sp-T-sp-T-sp-T-sp-T-sp-T-sp-G-sp-T-sp-T-sp-[2'-O-(2-methoxyethyl)]m5rC-[2'-O-(2-methoxyethyl)]m5rU-[2'-O-(2-methoxyethyl)]rG-sp-[2'-O-(2-methoxyethyl)]m5rC-sp-[2'-O-(2-methoxyethyl)]m5rC)
    1/16
  • DNA, d([2'-O-(2-methoxyethyl)]rA-sp-[2'-O-(2-methoxyethyl)]m5rC-[2'-O-(2-methoxyethyl)]rA-sp-[2'-O-(2-methoxyethyl)]rG-sp-[2'-O-(2-methoxyethyl)]rA-sp-T-sp-A-sp-T-sp-T-sp-T-sp-T-sp-T-sp-G-sp-T-sp-T-sp-[2'-O-(2-methoxyethyl)]m5rC-[2'-O-(2-methoxyethyl)]m5rU-[2'-O-(2-methoxyethyl)]rG-sp-[2'-O-(2-methoxyethyl)]m5rC-sp-[2'-O-(2-methoxyethyl)]m5rC)