2. Apoptosis
  3. Apoptosis
  4. Drozitumab

Drozitumab  (Synonyms: PRO 95780; rhuMAb-DR 5; Anti-Human DR5 Recombinant Antibody)

Cat. No.: HY-P99286

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Drozitumab (PRO 95780) is a human agonistic monoclonal antibody which binds the death receptor DR5. Drozitumab has potent antitumor activity against rhabdomyosarcoma.

For research use only. We do not sell to patients.

Drozitumab Chemical Structure

Drozitumab Chemical Structure

CAS No. : 912628-39-8

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Drozitumab Related Antibodies

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Description

Drozitumab (PRO 95780) is a human agonistic monoclonal antibody which binds the death receptor DR5. Drozitumab has potent antitumor activity against rhabdomyosarcoma[1][2][3].

In Vitro

Drozitumab selectively eliminates cancer stem cells (CSCs), resulting in tumor growth inhibition and even regression of pancreatic tumors[3].
Drozitumab induces apoptosis in mesenchymal TNBC cell lines but not in cell lines from other breast cancer subtypes[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Drozitumab Related Antibodies
Clinical Trial
Molecular Weight

143.1 (kDa)

CAS No.
SMILES

[Drozitumab]
Storage

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Purity & Documentation
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Drozitumab Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Drozitumab912628-39-8PRO 95780 rhuMAb-DR 5 Anti-Human DR5 Recombinant AntibodyPRO95780PRO-95780Apoptosiscancer stem cellsPancreatic cancerInhibitorinhibitorinhibit

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