eEF2K degrader-2
eEF2K degrader-2 (Compound C1) is a molecular glucose degrading agent that targets the eEF2K protein. eEF2K degrader-2 can significantly inhibit the proliferation, migration, invasion and induce apoptosis of triple negative breast cancer (TNBC) cells. eEF2K degrader-2 has no obvious organ toxicity or pathological damage. eEF2K degrader-2 can be used in the research of cancer such as breast cancer.
For research use only. We do not sell to patients.
- CAS No.: 1044797-96-7
- Formula: C27H29FN4O5
- Molecular Weight:508.54
-
Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
-
Biological Activity
-
Chemical Information
- Purity & Documentation
- References
-
Help & FAQs
Biological Activity
|
Cell Line
|
Type | Value | Description | References |
|---|---|---|---|---|
| MDA-MB-231 | IC50 |
131.2 nM
Compound: C1
|
Antitumor activity against human MDA-MB-231 cells assessed as inhibition of cell viability by measuring inhibition rate measured after 72 hrs by CCK-8 assay relative to control
Antitumor activity against human MDA-MB-231 cells assessed as inhibition of cell viability by measuring inhibition rate measured after 72 hrs by CCK-8 assay relative to control
|
[PMID: 39208364] |
Chemical Information
-
CAS No. 1044797-96-7
-
Molecular Weight 508.54
-
Formula C27H29FN4O5
-
SMILES
FC1=CC(CN(C2=O)C(C(C(N3CC(C(OCC)=O)CCC3)=O)=NN2C4=CC=C(C(C)=C4)C)=O)=CC=C1
-
Shipping
Room temperature in continental US; may vary elsewhere.
-
Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
eEF2K degrader-2 Related Classifications
HY-177720 Related Classifications
Powered by Bioz