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EGFR-IN-141

EGFR-IN-141 (Compound 8I) is the inhibitor for EGFR with an IC50 of 2.67 nM. EGFR-IN-141 exhibits cytotoxicity in cancer cell A549 with an IC50 of 13.75 μM. EGFR-IN-141 induces apoptosis and mitochondrial membrane depolarization, and exhibits potential antitumor efficacy.

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  • CAS No.: 3054263-27-0
  • Formula: C20H15FN8O2S2
  • Molecular Weight:482.51
  • Storage:

    Please store the product under the recommended conditions in the Certificate of Analysis.

  • EGFR-IN-141 Chemical Structure
    EGFR-IN-141 Chemical Structure
CAS No.: 3054263-27-0
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All EGFR Isoforms

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  • EGFR-IN-141 Chemical Structure
    EGFR-IN-141 Chemical Structure
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  • EGFR-IN-141