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Art. -Nr.: HY-163860

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EGFR-TK-IN-3

EGFR-TK-IN-3 (3) is an EGFR TK inhibitor, with an IC₅₀ of 2.33 μM against Erlotinib (HY-50896)-resistant A549 cells.

Nur für Forschungszwecke. Wir verkaufen nicht an Patienten.

Formel: C₃₈H₄₆FeN₆O₅
Molecular Weight:722.65

Speicherung:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (268 KB)

EGFR-TK-IN-3 Chemical Structure

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Preis

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Use of MCE Products

One-stop solution for XDC (ADC/PDC/RDC/ApDC/FDC/ISAC/VDC/SMDC)

Biologische Aktivität
- Beschreibung
- In Vitro
Chemical Information
Reinheit & Dokumentation
Verweise
Calculators
Help & FAQs
Classifications
Bioz

Biologische Aktivität

Beschreibung

EGFR-TK-IN-3 (3) is an EGFR TK inhibitor, with an IC₅₀ of 2.33 μM against Erlotinib (HY-50896)-resistant A549 cells^[1].

Alle EGFR Isoform-spezifische Produkte anzeigen :

In Vitro

The compound’s mechanism of anticancer action involves acombination of EGFR TK inhibitory activity and the capability to generatereactive oxygen species in lung cancer cells^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

Molecular Weight 722.65
Formel C₃₈H₄₆FeN₆O₅
SMILES

O=C(c1cccc1)CN2C=C(N=N2)C3=CC(NC4=NC=NC5=CC(OCCOC)=C(C=C54)OCCOC)=CC=C3.CC.CC.c6cccc6.[Fe]
Versand

Room temperature in continental US; may vary elsewhere.
Speicherung

Please store the product under the recommended conditions in the Certificate of Analysis.

Reinheit & Dokumentation

Select Batch:

Reinheit: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (268 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

Verweise

[1]. Przemysław Biegański, et al. Organometallic–Erlotinib Conjugates Active against Lung Cancer Cells and as Emerging Virus Entry Inhibitors. Organometallics 2024.

Calculators

Molaritätsrechner

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Konzentration Konzentration

Volumen Volumen

Molecular Weight Molecular Weight

Verdünnungsrechner

Konzentration _{(Stammlösung)} × Volumen _{(Stammlösung)} = Konzentration _{(Ziellösung)} × Volumen _{(Ziellösung)}

Konzentration _{(Stammlösung)} Konzentration _{(Stammlösung)}

Volumen _{(Stammlösung)} Volumen _{(Stammlösung)}

Konzentration _{(Ziellösung)} Konzentration _{(Ziellösung)}

Volumen _{(Ziellösung)} Volumen _{(Ziellösung)}

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Bioz

Keywords

MOQ

Minimum order quantity

100 mg

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