2. Apoptosis
  3. TNF Receptor
  4. EJMC-1

EJMC-1 is a moderately potent TNF-α inhibitor with an IC50 value of 42 μM.

For research use only. We do not sell to patients.

EJMC-1 Chemical Structure

EJMC-1 Chemical Structure

CAS No. : 397281-20-8

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Based on 1 publication(s) in Google Scholar

EJMC-1 Related Antibodies

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Description

EJMC-1 is a moderately potent TNF-α inhibitor with an IC50 value of 42 μM[1].

Molecular Weight

374.80

Formula

C17H11ClN2O4S
CAS No.
Appearance

Solid

Color

Light yellow to yellow

SMILES

O=C1NC2=CC=C(S(=O)(NC3=CC=C(C(Cl)=C3)O)=O)C4=C2C1=CC=C4
Shipping

Room temperature in continental US; may vary elsewhere.
Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : 125 mg/mL (333.51 mM; ultrasonic and warming and heat to 60°C; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.6681 mL 13.3404 mL 26.6809 mL
5 mM 0.5336 mL 2.6681 mL 5.3362 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

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g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation

Purity: 99.69%

COA (255 KB) HNMR (294 KB) LCMS (268 KB)

Handling Instructions (2659 KB)
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 2.6681 mL 13.3404 mL 26.6809 mL 66.7022 mL
5 mM 0.5336 mL 2.6681 mL 5.3362 mL 13.3404 mL
10 mM 0.2668 mL 1.3340 mL 2.6681 mL 6.6702 mL
15 mM 0.1779 mL 0.8894 mL 1.7787 mL 4.4468 mL
20 mM 0.1334 mL 0.6670 mL 1.3340 mL 3.3351 mL
25 mM 0.1067 mL 0.5336 mL 1.0672 mL 2.6681 mL
30 mM 0.0889 mL 0.4447 mL 0.8894 mL 2.2234 mL
40 mM 0.0667 mL 0.3335 mL 0.6670 mL 1.6676 mL
50 mM 0.0534 mL 0.2668 mL 0.5336 mL 1.3340 mL
60 mM 0.0445 mL 0.2223 mL 0.4447 mL 1.1117 mL
80 mM 0.0334 mL 0.1668 mL 0.3335 mL 0.8338 mL
100 mM 0.0267 mL 0.1334 mL 0.2668 mL 0.6670 mL
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EJMC-1 Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

EJMC-1397281-20-8EJMC1EJMC 1TNF ReceptorTumor Necrosis Factor ReceptorTNFRInhibitorinhibitorinhibit

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