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Cat. No.: HY-49537

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ER ligand-10

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Based on 1 Customer Validation

ER ligand-10 (Compound 11a) is a weak ERa and ERβ ligand, and shows weak estrogenic activity.

For research use only. We do not sell to patients.

CAS No.: 1075742-56-1
Formula: C₁₄H₁₃NO₃
Molecular Weight:243.26

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (268 KB)

ER ligand-10 Chemical Structure

CAS No.: 1075742-56-1

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Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- Description
- Cellular Effect
Chemical Information
Purity & Documentation
References
Calculators
Help & FAQs
Classifications
Bioz

Biological Activity

Description

ER ligand-10 (Compound 11a) is a weak ERa and ERβ ligand, and shows weak estrogenic activity^[1].

All Estrogen Receptor/ERR Isoforms :

Cellular Effect

Cell Line	Type	Value	Description	References
MCF7	EC₅₀	4.3 x 10^-5 M Compound: 11a	Estrogenic activity in human MCF7 cells assessed as cell proliferation after 6 days by WST8 assay Estrogenic activity in human MCF7 cells assessed as cell proliferation after 6 days by WST8 assay	[PMID: 18760603]
MCF7	EC₅₀	43 μM Compound: 11a	Estrogenic activity in human MCF7 cells assessed as cell proliferation after 6 days by WST8 assay Estrogenic activity in human MCF7 cells assessed as cell proliferation after 6 days by WST8 assay	[PMID: 18760603]

Chemical Information

CAS No. 1075742-56-1
Molecular Weight 243.26
Formula C₁₄H₁₃NO₃
SMILES

CC(N(C1=CC=C(O)C=C1)C2=CC=C(O)C=C2)=O
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (268 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Ohta K, et al. Promising core structure for nuclear receptor ligands: design and synthesis of novel estrogen receptor ligands based on diphenylamine skeleton. Bioorg Med Chem Lett. 2008 Sep 15;18(18):5050-3. [Content Brief]

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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Biological Activity
- Description
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References

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ER ligand-10

High-Throughput Bioactive Compound Library

All Estrogen Receptor/ERR Isoforms

Biological Activity

Chemical Information

Purity & Documentation

References

Calculators

Help & FAQs

ER ligand-10 Related Classifications

HY-49537 Related Classifications