ERRγ agonist-1
Based on 1 Customer Validation
ERRγ agonist-1 is a potent ERRγ agonist. ERRγ agonist-1 increases transcriptional activities of ERRγ. ERRγ agonist-1 has the potential for the research of neuropsychological disorders.
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研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- 純度: 98.02%
- CAS 番号: 3098411-72-1
- 分子式: C17H21N5O
- 分子量:311.38
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保管条件:
4°C, protect from light
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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生物活性
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化学情報
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溶剤 & 溶解度
- 純度とドキュメンテーション
- 参考文献
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Help & FAQs
生物活性
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ERRγ |
ERRγ agonist-1 (compound 5d) (5 μM; 3 days) significantly increases the expression of tyrosine hydroxylase (TH) and dopamine transporter (DAT), DAergic neuronal phenotypes (dopaminergic neuronal phenotype) in neuroblastoma SH-SY5Y cells[1].
ERRγ agonist-1 (5 μM; 3 days) induces DAergic neuronal phenotypes via the ERRγ-mediated up-regulation of CREB-signaling pathway[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
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Cell Line:SH-SY5Y cells
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Concentration:5 µM
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Incubation Time:3 days
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Result:Increased the DAergic neuronal-specific markers, TH and DAT in neuroblastoma SH-SY5Y cells.
化学情報
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CAS 番号 3098411-72-1
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性状 Solid
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分子量 311.38
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分子式 C17H21N5O
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Color Light yellow to yellow
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SMILES
CCCN(C1=CC=C(C=C1)/C=N/NC(C2=CC=C(N=C2)N)=O)C
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
4°C, protect from light
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
溶剤 & 溶解度
DMSO : 25 mg/mL (80.29 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
純度とドキュメンテーション
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データシート (269 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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取扱説明書 (2659 KB)
参考文献
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 3.2115 mL | 16.0576 mL | 32.1151 mL | 80.2878 mL |
| 5 mM | 0.6423 mL | 3.2115 mL | 6.4230 mL | 16.0576 mL | |
| 10 mM | 0.3212 mL | 1.6058 mL | 3.2115 mL | 8.0288 mL | |
| 15 mM | 0.2141 mL | 1.0705 mL | 2.1410 mL | 5.3525 mL | |
| 20 mM | 0.1606 mL | 0.8029 mL | 1.6058 mL | 4.0144 mL | |
| 25 mM | 0.1285 mL | 0.6423 mL | 1.2846 mL | 3.2115 mL | |
| 30 mM | 0.1071 mL | 0.5353 mL | 1.0705 mL | 2.6763 mL | |
| 40 mM | 0.0803 mL | 0.4014 mL | 0.8029 mL | 2.0072 mL | |
| 50 mM | 0.0642 mL | 0.3212 mL | 0.6423 mL | 1.6058 mL | |
| 60 mM | 0.0535 mL | 0.2676 mL | 0.5353 mL | 1.3381 mL | |
| 80 mM | 0.0401 mL | 0.2007 mL | 0.4014 mL | 1.0036 mL |
ERRγ agonist-1 関連分類
HY-145848 関連分類
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