ERα antagonist 2
ERα antagonist 2 (Compound 5b) is an ER-α antagonist with an IC50 value of 1729 nM. ERα antagonist 2 exhibits significant inhibitory activity against breast cancer cell lines, and is still effective against ER-negative cells (MDA-MB-231), suggesting the existence of ER-independent pathways. ERα antagonist 2 can be used for the study of breast cancer.
For research use only. We do not sell to patients.
- Formula: C46H38N6O4S2
- Molecular Weight:802.96
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
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ERα 1729 nM (IC50) |
Chemical Information
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Molecular Weight 802.96
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Formula C46H38N6O4S2
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SMILES
CC(C=C1)=CC=C1S(N(C(C2=CN(CC3=CC=CC=C3)C4=C2C=CC=C4)=NN5S(C6=CC=C(C)C=C6)(=O)=O)N=C5C7=CN(C8=C7C=CC=C8)CC9=CC=CC=C9)(=O)=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
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