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United States

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Referencia número: HY-160440A

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VU6021625

VU6021625 is a selective antagonist muscarinic acetylcholine receptors (mAChRs), with the IC₅₀ value of 0.44 nM, 57 nM for human M4 and rat M4, respectively.

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No. CAS: 2803696-99-1
Fòrmula: C₂₅H₃₂N₆O
Peso molecular:432.56

Almacenamiento:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (265 KB)

VU6021625 Chemical Structure

No. CAS: 2803696-99-1

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Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Actividad biológica

Descripciòn

VU6021625 is a selective antagonist muscarinic acetylcholine receptors (mAChRs), with the IC₅₀ value of 0.44 nM, 57 nM for human M4 and rat M4, respectively^[1].

Ver todos los productos específicos de isoformas mAChR :

Chemical Information

No. CAS 2803696-99-1
Peso molecular 432.56
Fòrmula C₂₅H₃₂N₆O
SMILES

[H][C@@](C1)(CN(C2)CC3CCOCC3)[C@@]2([H])C[C@H]1NC4=CC=C(C5=CC6=CN(C)N=C6C=C5)N=N4
Envío

Room temperature in continental US; may vary elsewhere.
Almacenamiento

Please store the product under the recommended conditions in the Certificate of Analysis.

Protocolo

All Cell Biology

Cell Cytotoxicity Assay
Cytotoxicity assays are usually based on the assessment of cell membrane damage, which can also be indirectly detected by measuring cell viability. Detection methods include MTT assay, CKK-8 assay, LDH assay and ATP assay, etc.

Pureza y Documentación

Select Batch:

Pureza: 99.98%

Assay: 99.98%

ee.: 99.98%

Ficha de datos (265 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Instrucciones de manejo (2659 KB)

Referencias

[1]. Mark S Moehle, et al. Discovery of the First Selective M4 Muscarinic Acetylcholine Receptor Antagonists with in Vivo Antiparkinsonian and Antidystonic Efficacy. ACS Pharmacol Transl Sci. 2021 Aug 2;4(4):1306-1321. [Content Brief]

Calculators

Calculadora de molaridad

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Calculadora de dilución

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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MOQ

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100 mg

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