Ethotoin
Based on 2 publication(s) in Google Scholar
Ethotoin (Peganone) is an orally active anticonvulsant agent used in epilepsy research, Ethotoin is a hydantoin, similar to phenytoin.
For research use only. We do not sell to patients.
- Purity: 99.61%
- CAS No.: 86-35-1
- Formula: C11H12N2O2
- Molecular Weight:204.23
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Storage:
4°C, protect from light
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
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Publications Citing Use of MedChemExpress (MCE) Ethotoin
More
Biological Activity
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
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Animal Model:Pregnant Sprague-Dawley CD rats[2]
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Dosage:600 mg/kg
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Administration:Oral gavage; 600 mg/kg; once
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Result:Preweaning mortality for Ethotoin was 2.0%, Ethotoin -exposed animals weighed approximately 6.6% less than controls.
Chemical Information
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CAS No. 86-35-1
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Appearance Solid
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Molecular Weight 204.23
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Formula C11H12N2O2
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Color White to off-white
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SMILES
O=C1N(CC)C(C(C2=CC=CC=C2)N1)=O
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Synonyms
Peganone
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
4°C, protect from light
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
Publications (2)
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Journal Impact Factor
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Most Recent
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Cell Death Dis
2025 Jun 2;16(1):426. PMID: 40456737 -
Toxicol Lett
Discovery of non-steroidal aldo-keto reductase 1D1 inhibitors through automated screening and in vitro evaluation. [Abstract]2025 Apr:406:31-37. PMID: 39988211
Solvent & Solubility
DMSO : ≥ 100 mg/mL (489.65 mM; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
* "≥" means soluble, but saturation unknown.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (276 KB)
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SDS (392 KB)
- English - EN (392 KB)
- Français - FR (392 KB)
- Deutsch - DE (392 KB)
- Norwegian - NO (392 KB)
- Español - ES (392 KB)
- Swedish - SV (392 KB)
- Italian - IT (392 KB)
- Korean - KR (392 KB)
- Portuguese - PT (392 KB)
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Handling Instructions (2659 KB)
References
[1]. A S Troupin, et al. Clinical pharmacology of mephenytoin and ethotoin. Ann Neurol. 1979 Nov;6(5):410-4. [Content Brief]
[2]. D R Minck, et al. Comparison of the behavioral teratogenic potential of phenytoin, mephenytoin, ethotoin, and hydantoin in rats. Teratology. 1991 Apr;43(4):279-93. [Content Brief]
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 4.8965 mL | 24.4823 mL | 48.9646 mL | 122.4116 mL |
| 5 mM | 0.9793 mL | 4.8965 mL | 9.7929 mL | 24.4823 mL | |
| 10 mM | 0.4896 mL | 2.4482 mL | 4.8965 mL | 12.2412 mL | |
| 15 mM | 0.3264 mL | 1.6322 mL | 3.2643 mL | 8.1608 mL | |
| 20 mM | 0.2448 mL | 1.2241 mL | 2.4482 mL | 6.1206 mL | |
| 25 mM | 0.1959 mL | 0.9793 mL | 1.9586 mL | 4.8965 mL | |
| 30 mM | 0.1632 mL | 0.8161 mL | 1.6322 mL | 4.0804 mL | |
| 40 mM | 0.1224 mL | 0.6121 mL | 1.2241 mL | 3.0603 mL | |
| 50 mM | 0.0979 mL | 0.4896 mL | 0.9793 mL | 2.4482 mL | |
| 60 mM | 0.0816 mL | 0.4080 mL | 0.8161 mL | 2.0402 mL | |
| 80 mM | 0.0612 mL | 0.3060 mL | 0.6121 mL | 1.5301 mL | |
| 100 mM | 0.0490 mL | 0.2448 mL | 0.4896 mL | 1.2241 mL |
Ethotoin Related Classifications
HY-B1642 Related Classifications
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