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Cat. No.: HY-121740

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FAUC-312

FAUC-312, a tetrahydropyrimidine, is a strong and highly selective dopamine D4 receptor partial agonist (K_i=1.5 nM).

For research use only. We do not sell to patients.

CAS No.: 562104-72-7
Formula: C₂₁H₂₆N₄
Molecular Weight:334.46

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (265 KB)

FAUC-312 Chemical Structure

CAS No.: 562104-72-7

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Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- Description
- IC₅₀ & Target
Chemical Information
Purity & Documentation
References
Calculators
Help & FAQs
Classifications
Bioz

Biological Activity

Description

FAUC-312, a tetrahydropyrimidine, is a strong and highly selective dopamine D4 receptor partial agonist (K_i=1.5 nM)^[1].

IC₅₀ & Target^[1]

Dopamine D4 receptor

1.5 nM (Ki)

Dopamine D1 receptor

29000 nM (Ki)

Dopamine D2 receptor

25000 nM (Ki)

Dopamine D3 receptor

13000 nM (Ki)

All Dopamine Receptor Isoforms :

Chemical Information

CAS No. 562104-72-7
Molecular Weight 334.46
Formula C₂₁H₂₆N₄
SMILES

C1(C2=CC=CC=C2)=NCC[C@H](N1)CN3CCN(CC3)C4=CC=CC=C4
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (265 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Jürgen Einsiedel, et al. Cyclic amidines as benzamide bioisosteres: EPC synthesis and SAR studies leading to the selective dopamine D4 receptor agonist FAUC 312. Bioorg Med Chem Lett. 2003 Mar 10;13(5):851-4. [Content Brief]

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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Biological Activity
- Description
- IC₅₀ & Target
Chemical Information
Purity & Documentation
References

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FAUC-312

All Dopamine Receptor Isoforms

Biological Activity

Chemical Information

Purity & Documentation

References

Calculators

Help & FAQs

FAUC-312 Related Classifications

HY-121740 Related Classifications