Folitixorin-d4
Folitixorin-d4 (5,10-Methylenetetrafolate-d4; ANX-510 (free acid)-d4) is the deuterium labeled Folitixorin (HY-14769). Folitixorin (5,10-methylenetetrahydrofolate) is a cofactor and an analog of leucovorin. Folitixorin is a promising agent for modulation of 5-FU cytotoxicity in adjuvant cancer research.
For research use only. We do not sell to patients.
- Formula: C20H17D4N7Na2O6
- Molecular Weight:505.43
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
All Endogenous Metabolite Isoforms
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Biological Activity
Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
1. This compound can be used as a tracer
2. This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
Chemical Information
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Unlabeled Cas 3432-99-3
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Molecular Weight 505.43
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Formula C20H17D4N7Na2O6
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SMILES
O=C1C2=C(NCC3N2CN(C4=C([2H])C([2H])=C(C(N[C@H](C(O[Na])=O)CCC(O[Na])=O)=O)C([2H])=C4[2H])C3)N=C(N)N1
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Synonyms
5,10-Methylenetetrafolate-d4; ANX-510 free acid-d4
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)