Cat. No.: HY-13012

RepSox

(Synonyms: E-616452; SJN 2511)

21 Cited Publications

Customer Review

Based on 21 publication(s) in Google Scholar

RepSox (E-616452) is a potent and selective transforming growth factor-beta receptor I/activin like kinase 5 (TGF-β-RI/ALK5) inhibitor. RepSox inhibits ALK5 autophosphorylation with an IC₅₀ value of 4 nM. RepSox can be used for the research of obesity and associated metabolic diseases such as type 2 diabetes.

For research use only. We do not sell to patients.

Purity: 99.92%
CAS No.: 446859-33-2
Formula: C₁₇H₁₃N₅
Molecular Weight:287.32

Storage:

Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 2 years , -20°C, 1 year

RepSox Chemical Structure

CAS No.: 446859-33-2

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Top Publications Citing

Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- Description
- IC₅₀ & Target
- Cellular Effect
- In Vitro
Chemical Information
Publications (21)
Solvent & Solubility
- In Vitro
- In Vivo
Purity & Documentation
References
Help & FAQs
Bioz

Biological Activity

Description

IC₅₀ & Target

ALK5

4 nM (IC₅₀)

All TGF-β Receptor Isoforms :

Cellular Effect

Cell Line	Type	Value	Description	References
HepG2	IC₅₀	0.01 μM Compound: 19	Stimulation of Transforming growth factor beta receptor I kinase in HepG2 cells Stimulation of Transforming growth factor beta receptor I kinase in HepG2 cells	[PMID: 15317461]
K562	IC₅₀	>100 μM Compound: ALK5 inhibitor II	Cytotoxicity against human K562 cells assessed as decrease in cell proliferation after 72 hrs by calcein AM staining-based assay Cytotoxicity against human K562 cells assessed as decrease in cell proliferation after 72 hrs by calcein AM staining-based assay	[PMID: 28135685]
MCF7	IC₅₀	>100 μM Compound: ALK5 inhibitor II	Cytotoxicity against human MCF7 cells assessed as decrease in cell proliferation after 72 hrs by calcein AM staining-based assay Cytotoxicity against human MCF7 cells assessed as decrease in cell proliferation after 72 hrs by calcein AM staining-based assay	[PMID: 28135685]
Sf9	IC₅₀	0.004 μM Compound: 19	Inhibition of recombinant Activin A receptor type II-like kinase (ALK5) expressed in baculovirus/Sf9 cells Inhibition of recombinant Activin A receptor type II-like kinase (ALK5) expressed in baculovirus/Sf9 cells	[PMID: 15317461]

In Vitro

RepSox (compound 19) inhibits ALK5 autophosphorylation with an IC₅₀ value of 4 nM^[1].
RepSox (0-10?μM; 0-8 days) induces adipogenesis from mouse embryonic fibroblasts (MEFs) in fibroblast culture medium^[2].
RepSox (0-10?μM; 0-8 days) promotes the differentiation of the brown fat precursor cells and induce browning of the white fat precursor cells^[2].
RepSox(0-10?μM; 0-8 days) induces brown adipogenesis in primary mouse fibroblasts and fat precursor cells^[2].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Western Blot Analysis^[2]

Cell Line:

Mouse embryonic fibroblasts (MEFs)
Concentration:

3 μM
Incubation Time:

0-8 days
Result:

Showed upregulation of UCP1 protein levels.

Immunofluorescence^[2]

Cell Line:

MEFs
Concentration:

3 μM
Incubation Time:

0-8 days
Result:

Increased the number of mitochondria in MEF-derived adipocytes and significantly increased UCP1 levels.

RT-PCR^[2]

Cell Line:

MEFs
Concentration:

3 μM
Incubation Time:

0-8 days
Result:

Induced the activation of a network of genes controlling adipogenesis, energy expenditure, and the thermogenic program in MEFs.

Chemical Information

CAS No. 446859-33-2
Appearance Solid
Molecular Weight 287.32
Formula C₁₇H₁₃N₅
Color Light brown to yellow
SMILES

CC1=NC(C2=NNC=C2C3=NC4=CC=CN=C4C=C3)=CC=C1
Synonyms

E-616452; SJN 2511
Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Powder	-20°C	3 years
	4°C	2 years
In solvent	-80°C	2 years
	-20°C	1 year

Publications (21)

All IFWBIn Vivo Efficacy Study2D/3D Cell Culture and DifferentiationRT-PCRFlow CytometryHistological Imaging/Staining

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Journal Impact Factor

Mil Med Res

Direct conversion of human fibroblasts into dopaminergic neuron-like cells using small molecules and protein factors. [Abstract]

2020 Nov 1;7(1):52. PMID: 33129359

RepSox purchased from MedChemExpress. Usage Cited in: Mil Med Res. 2020 Nov 1;7(1):52. [Abstract]

Chemical induction of human lung fetal IMR-90 fibroblasts into neuron-like cells. Representative microscopy images depicting the morphological changes after Repsox (2 μmol/L, 14 d) induction. Scale bars=100 μm.
Mil Med Res

Efficient and rapid conversion of human astrocytes and ALS mouse model spinal cord astrocytes into motor neuron-like cells by defined small molecules. [Abstract]

2020 Sep 6;7(1):42. PMID: 32892745
Adv Sci (Weinh)

Multicellular Bioprinting of Biomimetic Inks for Tendon-to-Bone Regeneration. [Abstract]

2023 Jul;10(21):e2301309. PMID: 37119499
Biomaterials

Chemical induced conversion of mouse fibroblasts and human adipose-derived stem cells into skeletal muscle-like cells. [Abstract]

2018 Dec 6;193:30-46. PMID: 30554025

RepSox purchased from MedChemExpress. Usage Cited in: Biomaterials. 2018 Dec 6;193:30-46. [Abstract]

Generation of RepSox (10 μM, 6 d) induced skeletal muscle like cells (CiSMLC) from mouse embryonic fibroblasts (MEFs). Immunohistochemical detection of CiSMLC with various skeletal muscle markers: MHC (MF20) and MyoD (Upper panel), α-actinin and its overlap with phase contrast image (middle panel), and Myogenin and its overlap with phase contrast images (lower panel). Magnified images in the inset are used to depict the detailed localization and co-expression and of these markers. All scale bars: 100 μm.

RepSox purchased from MedChemExpress. Usage Cited in: Biomaterials. 2018 Dec 6;193:30-46. [Abstract]

Generation of RepSox (10 μM, 6 d) induced skeletal muscle like cells (CiSMLC) from mouse embryonic fibroblasts (MEFs). Semi-quantitative RT-PCR analysis of various skeletal specific markers.

RepSox purchased from MedChemExpress. Usage Cited in: Biomaterials. 2018 Dec 6;193:30-46. [Abstract]

Representative flow cytometry analysis of α-actinin positive cells upon 4-factor (including RepSox 10 μM) treatment for indicated times (6-15 d).
Sci Adv

Chemical conversion of human epidermal stem cells into intestinal goblet cells for modeling mucus-microbe interaction and therapy. [Abstract]

2021 Apr 14;7(16):eabb2213. PMID: 33853767

RepSox purchased from MedChemExpress. Usage Cited in: Sci Adv. 2021 Apr 14;7(16):eabb2213. [Abstract]

Western blotting of the control hESC and the RCBB (including 5 μM Repsox, 6-8 d)-induced cells.
Nano Today

2025 Apr.
Acta Pharmacol Sin

In situ reprogramming of cardiac fibroblasts into cardiomyocytes in mouse heart with chemicals. [Abstract]

2024 Nov;45(11):2290-2299. PMID: 38890526

RepSox purchased from MedChemExpress. Usage Cited in: Acta Pharmacol Sin. 2024 Nov;45(11):2290-2299. [Abstract]

Schemes of generating Fsp1-Cre:R26R-loxp-tdTomato mice and drug treatment to induce in situ transdifferentiation. Fsp1-Cre mice were crossed with R26Rloxp-tdTomato mice in which the expression of tdTomato is prevented by a loxP-flanked STOP cassette. The F1 mice would have the red fluorescent protein tdTomato expressed specifically in the fibroblasts. CRFVPTM were given once a week for 6 weeks. Immunofluorescence staining of the cryosections of the hearts from Fsp1-Cre:R26R-loxp-tdTomato mice treated with vehicle (b) or CRFVPTM (c) for 6 weeks. C: CHIR99021, 14 mg/kg; R: RepSox, 8.6 mg/kg; F: Forskolin, 61.6 mg/kg; V: VPA, 250 mg/kg; T: TTNPB, 1 mg/kg and M: Rolipram, 2.5 mg/kg; P: Parnate, 2.7 mg/kg, CRFTM by oral gavage and VP by intraperitoneal injection once a week for 6 weeks in mice at about 8 weeks of age.

RepSox purchased from MedChemExpress. Usage Cited in: Acta Pharmacol Sin. 2024 Nov;45(11):2290-2299. [Abstract]

Whole-heart imaging with light-sheet fluorescence microscopy after tissue clearing of the hearts from Fsp1-Cre:R26R-loxp-tdTomato mice treated with vehicle (a) or CRFVPTM (b). (C: CHIR99021, 14 mg/kg; R: RepSox, 8.6 mg/kg; F: Forskolin, 61.6 mg/kg; V: VPA, 250 mg/kg; T: TTNPB, 1 mg/kg and M: Rolipram, 2.5 mg/kg; P: Parnate, 2.7 mg/kg, CRFTM by oral gavage and VP by intraperitoneal injection once a week for 6 weeks in mice at about 8 weeks of age).

RepSox purchased from MedChemExpress. Usage Cited in: Acta Pharmacol Sin. 2024 Nov;45(11):2290-2299. [Abstract]

a Schemes of obtaining PDGFRα-DreER:R26R-rox-tdTomato mice and drug treatment to induce in situ cardiac reprogramming in PDGFRα-DreER:R26R-roxtdTomato mice. PDGFRα-DreER mice were mated with R26R-rox-tdTomato mice in which the expression of tdTomato is prevented by a roxflanked STOP cassette. The expression of tdTomato in fibroblasts was turned on by tamoxifen treatment. CRFVPTM were given once a week for 6 weeks. b Body weigh change of the mice after chemical treatment. Immunofluorescence staining of the cryosections of the hearts from PDGFRα-DreER:R26R-rox-tdTomato mice treated with vehicle (c) or CRFVPTM (d) for 6 weeks. (C: CHIR99021, 14 mg/kg; R: RepSox, 8.6 mg/kg; F: Forskolin, 61.6 mg/kg; V: VPA, 250 mg/kg; T: TTNPB, 1 mg/kg and M: Rolipram, 2.5 mg/kg; P: Parnate, 2.7 mg/kg, CRFTM by oral gavage and VP by intraperitoneal injection once a week for 6 weeks in mice at about 8 weeks of age).

RepSox purchased from MedChemExpress. Usage Cited in: Acta Pharmacol Sin. 2024 Nov;45(11):2290-2299. [Abstract]

Immunofluorescence staining of α-actinin in cryosections of hearts from Fsp1-Cre:R26R-loxp-tdTomato mice treated with 7 C cocktail (CRFVPTM) or cocktails by removing 1 compound from 7 C (7C-X) for 6 weeks in vivo with Fsp1-Cre:R26R-loxp-tdTomato mice. (C: CHIR99021, 14 mg/kg; R: RepSox, 8.6 mg/kg; F: Forskolin, 61.6 mg/kg; V: VPA, 250 mg/kg; T: TTNPB, 1 mg/kg and M: Rolipram, 2.5 mg/kg; P: Parnate, 2.7 mg/kg, CRFTM by oral gavage and VP by intraperitoneal injection once a week for 6 weeks in mice at about 8 weeks of age).
Biomed Pharmacother

Mechanical stress protects against chondrocyte pyroptosis through TGF-β1-mediated activation of Smad2/3 and inhibition of the NF-κB signaling pathway in an osteoarthritis model. [Abstract]

2023 Mar:159:114216. PMID: 36634591
Stem Cell Res Ther

Characterisation of extraembryonic endoderm-like cells from mouse embryonic fibroblasts induced using chemicals alone. [Abstract]

2020 Apr 16;11(1):157. PMID: 32299508
J Tissue Eng

Extracellular matrix-derived peptide stimulates the generation of endocrine progenitors and islet organoids from iPSCs. [Abstract]

2023 Jul 8:14:20417314231185858. PMID: 37435573
Cell Rep

ASCL1 characterizes adrenergic neuroblastoma via its pioneer function and cooperation with core regulatory circuit factors. [Abstract]

2023 Dec 5;42(12):113541. PMID: 38060444
J Biol Eng

Tissue engineering RPE sheet derived from hiPSC-RPE cell spheroids supplemented with Y-27632 and RepSox. [Abstract]

2024 Jan 16;18(1):7. PMID: 38229139
Int J Mol Sci

Small Molecules Temporarily Induce Neuronal Features in Adult Canine Dermal Fibroblasts. [Abstract]

2023 Oct 31;24(21):15804. PMID: 37958789
J Cell Mol Med

TGF-β isoforms inhibit hepatitis C virus propagation in transforming growth factor beta/SMAD protein signalling pathway dependent and independent manners. [Abstract]

2021 Apr;25(7):3498-3510. PMID: 33682288
Biomedicines

Generation of a Pure Culture of Neuron-like Cells with a Glutamatergic Phenotype from Mouse Astrocytes. [Abstract]

2022 Apr 18;10(4):928. PMID: 35453678
Biomedicines

Exosome-Mediated Differentiation of Mouse Embryonic Fibroblasts and Exocrine Cells into β-Like Cells and the Identification of Key miRNAs for Differentiation. [Abstract]

2020 Nov 9;8(11):485. PMID: 33182285
Genes (Basel)

CHIR99021 and Brdu Are Critical in Chicken iPSC Reprogramming via Small-Molecule Screening. [Abstract]

2024 Sep 13;15(9):1206. PMID: 39336797
Int J Stem Cells

Strategic Application of Epigenetic Regulators for Efficient Neuronal Reprogramming of Human Fibroblasts. [Abstract]

2023 May 30;16(2):156-167. PMID: 36823979
Brain Science Advances

2022 Feb.
ACS Comb Sci

Benzimidazolyl-pyrazolo[3,4- b]pyridinones, Selective Inhibitors of MOLT-4 Leukemia Cell Growth and Sea Urchin Embryo Spiculogenesis: Target Quest. [Abstract]

2019 Dec 9;21(12):805-816. PMID: 31689077
Oncotarget

Phorbol esters dPPA/dPA promote furin expression involving transcription factor CEBPβ in neuronal cells. [Abstract]

2017 Jun 19;8(36):60159-60172. PMID: 28947961

RepSox purchased from MedChemExpress. Usage Cited in: Oncotarget. 2017 Jun 19;8(36):60159-60172. [Abstract]

SH-SY5Y (A) and HEK293 cells (B) are treated with 25 μM RepSox (Rep) in absence or presence of dPA or dPPA for 72 h, and the Western blotting results show that dPA or dPPA increases the expression in the presence of RepSox. RepSox does not cause significant alteration of furin protein compared to control. The expression of furin remains significantly increased after dPA or dPPA in the presence of RepSox.

Solvent & Solubility

In Vitro:

DMSO : 33.33 mg/mL (116.00 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

View the Complete Stock Solution Preparation Table

Preparing Stock Solutions

View the Complete Stock Solution Preparation Table

Concentration Solvent Mass

1 mg

5 mg

10 mg

Concentration

Solvent

Mass

1 mM

3.4804 mL

17.4022 mL

34.8044 mL

5 mM

0.6961 mL

3.4804 mL

6.9609 mL

10 mM

0.3480 mL

1.7402 mL

3.4804 mL

Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.

Storage method and period of stock solution: -80°C, 2 years; -20°C, 1 year. When stored at -80°C, please use it within 2 years. When stored at -20°C, please use it within 1 year.

Molarity Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Concentration Concentration

Volume Volume

Molecular Weight Molecular Weight

Dilution Calculator

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

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Volume _(start) Volume _(start)

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In Vivo:

Select the appropriate dissolution method based on your experimental animal and administration route.

Stock Solution Working Solution

For the following dissolution methods, please ensure to first prepare a clear stock solution using an In Vitro approach and then sequentially add co-solvents:
To ensure reliable experimental results, the clarified stock solution can be appropriately stored based on storage conditions. As for the working solution for In Vivo experiments, it is recommended to prepare freshly and use it on the same day.
The percentages shown for the solvents indicate their volumetric ratio in the final prepared solution. If precipitation or phase separation occurs during preparation, heat and/or sonication can be used to aid dissolution.

Protocol 1

Add each solvent one by one: 10% DMSO 40% PEG300 5% Tween-80 45% Saline

Solubility: ≥ 7.5 mg/mL (26.10 mM); Clear solution

This protocol yields a clear solution of ≥ 7.5 mg/mL (saturation unknown).

Taking 1 mL working solution as an example, add 100 μL DMSO stock solution (75.0 mg/mL) to 400 μL PEG300, and mix evenly; then add 50 μL Tween-80 and mix evenly; then add 450 μL Saline to adjust the volume to 1 mL.

Protocol 2

Add each solvent one by one: 10% DMSO 90% (20% SBE-β-CD in Saline)

Solubility: ≥ 7.5 mg/mL (26.10 mM); Clear solution

This protocol yields a clear solution of ≥ 7.5 mg/mL (saturation unknown).

Taking 1 mL working solution as an example, add 100 μL DMSO stock solution (75.0 mg/mL) to 900 μL 20% SBE-β-CD in Saline, and mix evenly.

Protocol 3

Add each solvent one by one: 5% DMSO 40% PEG300 5% Tween-80 50% Saline

Solubility: ≥ 1.67 mg/mL (5.81 mM); Clear solution

Protocol 4

Add each solvent one by one: 5% DMSO 95% (20% SBE-β-CD in Saline)

Solubility: ≥ 1.67 mg/mL (5.81 mM); Clear solution

Protocol 5

Add each solvent one by one: 1% DMSO 99% Saline

Solubility: ≥ 0.33 mg/mL (1.15 mM); Clear solution

In Vivo Dissolution Calculator

Please enter the basic information of animal experiments:

Dosage Dosage
mg/kg
Animal Weight (Per Animal) Animal Weight (Per Animal)
g
Dosing Volume (Per Animal) Dosing Volume (Per Animal)
μL
Number of Animals Number of Animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.

Please enter your animal formula composition:

%
DMSO +

Recommended: Keep the proportion of DMSO in working solution below 2% if your animal is weak.
%
+
+
%
Tween-80 + +
%
Saline +

The co-solvents required include: DMSO, . All of co-solvents are available by MedChemExpress (MCE). , Tween 80. All of co-solvents are available by MedChemExpress (MCE).

Working solution concentration: 0.22 mg/mL

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (282 KB)
SDS (420 KB)
- English - EN (420 KB)
- Français - FR (420 KB)
- Deutsch - DE (420 KB)
- Norwegian - NO (420 KB)
- Español - ES (420 KB)
- Swedish - SV (420 KB)
- Italian - IT (420 KB)
- Portuguese - PT (420 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Gellibert F, et al. Identification of 1,5-naphthyridine derivatives as a novel series of potent and selective TGF-beta type I receptor inhibitors. J Med Chem. 2004 Aug 26;47(18):4494-506. [Content Brief]

[2]. Wan-Zhi Tu, et al. RepSox, a small molecule inhibitor of the TGFβ receptor, induces brown adipogenesis and browning of white adipocytes. Acta Pharmacol Sin. 2019 Dec;40(12):1523-1531. [Content Brief]

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Complete Stock Solution Preparation Table

Storage method and period of stock solution: -80°C, 2 years; -20°C, 1 year. When stored at -80°C, please use it within 2 years. When stored at -20°C, please use it within 1 year.

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg
DMSO	1 mM	3.4804 mL	17.4022 mL	34.8044 mL	87.0110 mL
	5 mM	0.6961 mL	3.4804 mL	6.9609 mL	17.4022 mL
	10 mM	0.3480 mL	1.7402 mL	3.4804 mL	8.7011 mL
	15 mM	0.2320 mL	1.1601 mL	2.3203 mL	5.8007 mL
	20 mM	0.1740 mL	0.8701 mL	1.7402 mL	4.3505 mL
	25 mM	0.1392 mL	0.6961 mL	1.3922 mL	3.4804 mL
	30 mM	0.1160 mL	0.5801 mL	1.1601 mL	2.9004 mL
	40 mM	0.0870 mL	0.4351 mL	0.8701 mL	2.1753 mL
	50 mM	0.0696 mL	0.3480 mL	0.6961 mL	1.7402 mL
	60 mM	0.0580 mL	0.2900 mL	0.5801 mL	1.4502 mL
	80 mM	0.0435 mL	0.2175 mL	0.4351 mL	1.0876 mL
	100 mM	0.0348 mL	0.1740 mL	0.3480 mL	0.8701 mL

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RepSox

Kinase Inhibitor Library

Stem Cell Signaling Compound Library

TGF-beta/Smad Compound Library

Anti-Aging Compound Library

Reprogramming Compound Library

Anti-diabetic Compound Library

Anti-Pancreatic Cancer Compound Library

Anti-Obesity Compound Library

Angiogenesis-Related Compound Library

Anti-Colorectal Cancer Compound Library

Human Metabolite Library

Anti-Prostate Cancer Compound Library

Anti-Pulmonary Fibrosis Compound Library

Osteogenesis Compound Library

Cancer Stem Cells Compound Library

Heterocyclic Compound Library

Membrane Protein-targeted Compound Library

Membrane Receptor-targeted Compound Library

Highly Selective Inhibitors Library

Cytokine Inhibitors Library

Bioactive Compound Library Max

MCE Bioactive Compound Library

Bioactive Compound Library

Anti-Fibrosis Compound Library

High-Throughput Bioactive Compound Library

Mass Spectrometry Human Metabolite Library

Posttranslational Modification Library

Publications Citing Use of MedChemExpress (MCE) RepSox

All TGF-β Receptor Isoforms

Biological Activity

Chemical Information

Publications (21)

Solvent & Solubility

Purity & Documentation

References

Help & FAQs

Complete Stock Solution Preparation Table

RepSox

Kinase Inhibitor Library

Stem Cell Signaling Compound Library

TGF-beta/Smad Compound Library

Anti-Aging Compound Library

Reprogramming Compound Library

Anti-diabetic Compound Library

Anti-Pancreatic Cancer Compound Library

Anti-Obesity Compound Library

Angiogenesis-Related Compound Library

Anti-Colorectal Cancer Compound Library

Human Metabolite Library

Anti-Prostate Cancer Compound Library

Anti-Pulmonary Fibrosis Compound Library

Osteogenesis Compound Library

Cancer Stem Cells Compound Library

Heterocyclic Compound Library

Membrane Protein-targeted Compound Library

Membrane Receptor-targeted Compound Library

Highly Selective Inhibitors Library

Cytokine Inhibitors Library

Bioactive Compound Library Max

MCE Bioactive Compound Library

Bioactive Compound Library

Anti-Fibrosis Compound Library

High-Throughput Bioactive Compound Library

Mass Spectrometry Human Metabolite Library

Posttranslational Modification Library

Publications Citing Use of MedChemExpress (MCE) RepSox

All TGF-β Receptor Isoforms

Biological Activity

Chemical Information

Publications (21)

Solvent & Solubility

Purity & Documentation

References

Help & FAQs

Complete Stock Solution Preparation Table

RepSox Related Classifications

Cat. No.: HY-13012