Oxacillin-d5
Oxacillin-d5 is the deuterium labeled Oxacillin. Oxacillin is an orally active synthetic penicillin with good bactericidal activity against staphylococci and other gram-positive pathogens.
For research use only. We do not sell to patients.
- Formula: C19H14D5N3O5S
- Molecular Weight:406.47
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
All Antibiotic Isoforms
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Biological Activity
Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
1. This compound can be used as a tracer
2. This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
Chemical Information
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Unlabeled Cas 66-79-5
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Molecular Weight 406.47
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Formula C19H14D5N3O5S
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SMILES
OC([C@@H]1N2[C@@](SC1(C)C)([H])[C@@H](C2=O)NC(C3=C(C)ON=C3C4=C([2H])C([2H])=C([2H])C([2H])=C4[2H])=O)=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216. [Content Brief]
[2]. KIRBY WM, et al. Oxacillin: laboratory and clinical evaluation. JAMA. 1962 Sep 1;181:739-44. [Content Brief]
[3]. Yurchenco JA, et al. Nafcillin and oxacillin: comparative antistaphylococcal activity in mice. J Antibiot (Tokyo). 1976 Apr29(4):460-5. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)