AVE-9488
Based on 1 Customer Validation
AVE-9488 is an eNOS enhancer with the activity of protecting the heart from ischemia-reperfusion injury. AVE-9488 can upregulate eNOS expression, increase NO production, reduce myocardial ischemia-reperfusion injury, and reduce the level of reactive oxygen species.
For research use only. We do not sell to patients.
- Purity: 99.77%
- CAS No.: 291756-32-6
- Formula: C16H14FNO
- Molecular Weight:255.29
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Storage:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
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eNOS |
Chemical Information
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CAS No. 291756-32-6
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Appearance Solid
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Molecular Weight 255.29
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Formula C16H14FNO
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Color White to off-white
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SMILES
O=C(NC1CC2=C(C=CC=C2)C1)C3=CC=C(F)C=C3
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Solvent & Solubility
DMSO : 25 mg/mL (97.93 mM; ultrasonic and warming and heat to 60°C; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (269 KB)
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SDS (251 KB)
- English - EN (251 KB)
- Français - FR (251 KB)
- Deutsch - DE (251 KB)
- Norwegian - NO (251 KB)
- Español - ES (251 KB)
- Swedish - SV (251 KB)
- Italian - IT (251 KB)
- Korean - KR (251 KB)
- Portuguese - PT (251 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 3.9171 mL | 19.5856 mL | 39.1711 mL | 97.9278 mL |
| 5 mM | 0.7834 mL | 3.9171 mL | 7.8342 mL | 19.5856 mL | |
| 10 mM | 0.3917 mL | 1.9586 mL | 3.9171 mL | 9.7928 mL | |
| 15 mM | 0.2611 mL | 1.3057 mL | 2.6114 mL | 6.5285 mL | |
| 20 mM | 0.1959 mL | 0.9793 mL | 1.9586 mL | 4.8964 mL | |
| 25 mM | 0.1567 mL | 0.7834 mL | 1.5668 mL | 3.9171 mL | |
| 30 mM | 0.1306 mL | 0.6529 mL | 1.3057 mL | 3.2643 mL | |
| 40 mM | 0.0979 mL | 0.4896 mL | 0.9793 mL | 2.4482 mL | |
| 50 mM | 0.0783 mL | 0.3917 mL | 0.7834 mL | 1.9586 mL | |
| 60 mM | 0.0653 mL | 0.3264 mL | 0.6529 mL | 1.6321 mL | |
| 80 mM | 0.0490 mL | 0.2448 mL | 0.4896 mL | 1.2241 mL |
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