CycLuc1
Based on 3 publication(s) in Google Scholar
CycLuc1 is a blood-brain barrier permeable luciferase substrate that displays near-infrared (NIR) emission with a peak luminescence wavelength of 599 nm. CycLuc1 can be used for in vivo bioluminescence imaging.
Para uso exclusivo en investigación. No vendemos a pacientes.
- Pureza: 99.72%
- No. CAS: 1247879-16-8
- Fòrmula: C13H11N3O2S2
- Peso molecular:305.38
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Almacenamiento:
4°C, protect from light
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Actividad biológica
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Chemical Information
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Solvente y solubilidad
- Pureza y Documentación
- Referencias
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Help & FAQs
Publications Citing Use of MedChemExpress (MCE) CycLuc1
More
Customer Validation & Images
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Bio/Physico-chemical Assay
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In Vivo Imaging
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Bio/Physico-chemical Assay
Actividad biológica
Luciferase[1]
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
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Animal Model:Mouse xenograft tumor models[2]
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Dosage:0.05, 0.5, 1, 5 mM, 100 μL
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Administration:i.p.
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Result:Yielded a >10-fold higher bioluminescent signal than could be obtained from D-luciferin injection at equivalent doses.
Chemical Information
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No. CAS 1247879-16-8
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Appearance Solid
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Peso molecular 305.38
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Fòrmula C13H11N3O2S2
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Color Yellow to brown
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SMILES
O=C([C@@H]1N=C(C2=NC3=CC4=C(NCC4)C=C3S2)SC1)O
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Envío
Room temperature in continental US; may vary elsewhere.
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Almacenamiento
4°C, protect from light
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
Publications (3)
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Journal Impact Factor
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Most Recent
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Sci Rep
Real-time bioluminescence imaging of mycobacteria with Akaluc: a novel method for monitoring drug efficacy. [Abstract]2026 May 15;16(1):15193. PMID: 42151204 -
Microbiol Spectr
Near-infrared in vivo imaging system for dynamic visualization of lung-colonizing bacteria in mouse pneumonia. [Abstract]2024 Nov 5;12(11):e0082824. PMID: 39287455
CycLuc1 purchased from MedChemExpress. Usage Cited in: Microbiol Spectr. 2024 Nov 5;12(11):e0082824. [Abstract]
The luminescence signals of the ATCC 17978-Luc strain with CycLuc1 (10 μM) was 9.0 × 105 RLU.
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CycLuc1 purchased from MedChemExpress. Usage Cited in: bioRxiv. 2023 Apr 29.
CycLuc1 (5 mM, 10 μL/g) injection improved signal detection in the head in CAG-LSL-oFluc mice.
CycLuc1 purchased from MedChemExpress. Usage Cited in: bioRxiv. 2023 Apr 29.
RLU of the tissue extracts of oFluc from C57BL/6 mice supplemented with CycLuc1 (1 mM).
Solvente y solubilidad
DMSO : 50 mg/mL (163.73 mM; ultrasonic and warming and heat to 60°C; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Pureza y Documentación
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Ficha de datos (273 KB)
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SDS (393 KB)
- English - EN (393 KB)
- Français - FR (393 KB)
- Deutsch - DE (393 KB)
- Norwegian - NO (393 KB)
- Español - ES (393 KB)
- Swedish - SV (393 KB)
- Italian - IT (393 KB)
- Korean - KR (393 KB)
- Portuguese - PT (393 KB)
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Instrucciones de manejo (2659 KB)
Referencias
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 3.2746 mL | 16.3730 mL | 32.7461 mL | 81.8652 mL |
| 5 mM | 0.6549 mL | 3.2746 mL | 6.5492 mL | 16.3730 mL | |
| 10 mM | 0.3275 mL | 1.6373 mL | 3.2746 mL | 8.1865 mL | |
| 15 mM | 0.2183 mL | 1.0915 mL | 2.1831 mL | 5.4577 mL | |
| 20 mM | 0.1637 mL | 0.8187 mL | 1.6373 mL | 4.0933 mL | |
| 25 mM | 0.1310 mL | 0.6549 mL | 1.3098 mL | 3.2746 mL | |
| 30 mM | 0.1092 mL | 0.5458 mL | 1.0915 mL | 2.7288 mL | |
| 40 mM | 0.0819 mL | 0.4093 mL | 0.8187 mL | 2.0466 mL | |
| 50 mM | 0.0655 mL | 0.3275 mL | 0.6549 mL | 1.6373 mL | |
| 60 mM | 0.0546 mL | 0.2729 mL | 0.5458 mL | 1.3644 mL | |
| 80 mM | 0.0409 mL | 0.2047 mL | 0.4093 mL | 1.0233 mL | |
| 100 mM | 0.0327 mL | 0.1637 mL | 0.3275 mL | 0.8187 mL |
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