Copy Link Print Information

TBHQ

(Synonyms: tert-Butylhydroquinone)
129 Cited Publications
Revisión del cliente

Based on 129 publication(s) in Google Scholar

TBHQ (tert-Butylhydroquinone) is a widely used Nrf2 activator, protects against Doxorubicin (DOX)-induced cardiotoxicity through activation of Nrf2. TBHQ (tert-Butylhydroquinone) is also an ERK activator; rescues Dehydrocorydaline (DHC)-induced cell proliferation inhibitionin melanoma.

Para uso exclusivo en investigación. No vendemos a pacientes.

  • Pureza: 99.86%
  • No. CAS: 1948-33-0
  • Fòrmula: C10H14O2
  • Peso molecular:166.22
  • Almacenamiento:

    Store at room temperature 3 years.

    In solvent   -80°C, 2 years , -20°C, 1 year
  • TBHQ Chemical Structure
    TBHQ Chemical Structure
  • Experimental Validation Results for TBHQ
  • Experimental Validation Results for TBHQ
  • Experimental Validation Results for TBHQ
  • Experimental Validation Results for TBHQ
  • Experimental Validation Results for TBHQ
  • Experimental Validation Results for TBHQ
  • Experimental Validation Results for TBHQ
No. CAS: 1948-33-0
Tamaño
Precio
Stock
Cantidad
Amount: USD 0.00
Please select quantity
or
or

* Seleccione Cantidad antes de agregar artículos.

To place orders, for customer services and technical support, please contact: MedChemExpress USA

Tel: 609-228-6898 E-mail: [email protected] [email protected]

Data Download
Other Forms of TBHQ:

To place orders, for customer services and technical support, please contact:

609-228-6898
[email protected] [email protected]
Encuentre su distribuidor local Your local distributor: Hycultec GmbHHycultec
  • Actividad biológica
  • Chemical Information
  • Solvente y solubilidad
  • Pureza y Documentación
  • Referencias
  • Help & FAQs
You May Still Need
Top Publications Citing

Use of MCE Products

Publications Citing Use of MedChemExpress (MCE) TBHQ

More
Customer Validation & Images
RT-PCRWBIF
  • WB
  • RT-PCR
  • WB
  • IF
  • WB
  • WB
  • WB

Ver todos los productos específicos de isoformas ERK

More
Keywords
MOQ
Minimum order quantity
100 mg

Obtener un presupuesto En stock

Other size
Obtener un presupuesto
Please select quantity
Amount: USD 0.00
Sign in to MedChemExpress Inicie sesiòn
Registrar
Sign in to MedChemExpress
Registrar una cuenta nueva

At least 6 characters

Personalize your experience, you are currently not signed in. For a better experience, please create an online profile, you can:

Obtain points redemption prizes
Check out faster
Add multiple shipping locations
View orders
Assay Types
  • TBHQ Chemical Structure
    TBHQ Chemical Structure
    1/16
  • 1/16

    TBHQ purchased from MedChemExpress. Usage Cited in: Adv Sci (Weinh). 2025 May 23:e04372. [Abstract]

    Customer Validation
     Protein levels of NRF, PIP5K1A and NQO1 in Hep3B cells treated with tBHQ (TBHQ; 50 μm) or SFN (5 μm) for 24h.

  • 1/16

    TBHQ purchased from MedChemExpress. Usage Cited in: Autophagy. 2025 Feb;21(2):407-423. [Abstract]

    Customer Validation
     RT-PCR to measure expression of NFE2L2 targets in A549 cells infected with WT or ΔS legionella for 6 h in presence of 10 µm tBHQ or ML385.

  • 1/16

    TBHQ purchased from MedChemExpress. Usage Cited in: Nat Commun. 2023 May 13;14(1):2756. [Abstract]

    Customer Validation
     TBHQ (20 μM; 24 h) activates ERK and modestly increases p-EphA2 (Ser897) levels in HL-7702 cells. However, when combined with regorafenib, TBHQ fails to rescue the inhibition of p-EphA2. Under TBHQ treatment, regorafenib still inhibits EphA2 phosphorylation and reduces p-ERK levels.

  • 1/16

    TBHQ purchased from MedChemExpress. Usage Cited in: Nat Commun. 2023 Apr 10;14(1):2004. [Abstract]

    Customer Validation
     TBHQ (1 μM) further promotes TNC (0.5 μg/mL)-induced neurite anomalous bifurcation.

  • 1/16

    TBHQ purchased from MedChemExpress. Usage Cited in: J Nanobiotechnology. 2022 Jun 11;20(1):270. [Abstract]

    Customer Validation
     Immunoblotting analysis and quantification of NRF2 half-life in CuONPs-treated WT or ATG5-KO HUVECs cells. Cells were treated with TBHQ (tBHQ; 10 μM) and CuONPs (20 μg/ml) for 9 h, and then treated with CHX (50 μg/ml) for 0, 1, 2, 3, 6, 9 h, respectively. β-Actin served as loading control.

  • 1/16

    TBHQ purchased from MedChemExpress. Usage Cited in: Front Pharmacol. 2018 Jun 6:9:540. [Abstract]

    Customer Validation
     BHQ promotes higher protein expression of Nrf2 in a time-dependent manner in neonatal rat cardiac fibroblasts (NRCF) while notably downregulated collagen I and collagen III.

  • 1/16

    TBHQ purchased from MedChemExpress. Usage Cited in: Biochem Biophys Res Commun. 2018 Jun 7;500(3):790-796. [Abstract]

    Customer Validation
     Macrophages are isolated from wild-type mice, treated with tBHQ (100 μM) or not, and induced for 3 h using LPS, IFN-g, IL-4 or IL-13. Western blot analysis of the expression of Nrf2, p65 subunit of NF-kB, phosphorylated p65 and PPARg in the cytoplasm and nucleus.

  • TBHQ