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Ac4ManNAz

17 Cited Publications
Revisión del cliente

Based on 17 publication(s) in Google Scholar

Ac4ManNAz can be taken up by cells and is an azide-containing metabolic glycoprotein labeling reagent that selectively modifies proteins. Commonly used for cell labeling, tracking and proteomic analysis. Ac4ManNAz contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. Ac4ManNAz can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN groups.

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  • Pureza: 99.94%
  • No. CAS: 1213701-11-1
  • Fòrmula: C16H22N4O10
  • Peso molecular:430.37
  • Almacenamiento:
    Powder   -20°C, 3 years ; In solvent   -80°C, 6 months , -20°C, 1 month
  • Ac4ManNAz Chemical Structure
    Ac4ManNAz Chemical Structure
  • Experimental Validation Results for Ac4ManNAz
  • Experimental Validation Results for Ac4ManNAz
  • Experimental Validation Results for Ac4ManNAz
  • Experimental Validation Results for Ac4ManNAz
  • Experimental Validation Results for Ac4ManNAz
No. CAS: 1213701-11-1
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  • Ac4ManNAz Chemical Structure
    Ac4ManNAz Chemical Structure
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    Ac4ManNAz purchased from MedChemExpress. Usage Cited in: Adv Mater. 2025 Jul 7:e2504733. [Abstract]

    Customer Validation
     Scheme illustration of the preparation of tumor-lysate pulsed DC vaccines (DCVs). BMDCs were incubated with 50 μM Ac4ManNAz and tumor lysates for 48 h.

  • 1/16

    Ac4ManNAz purchased from MedChemExpress. Usage Cited in: Int J Nanomedicine. 2025 Nov 26:20:14185-14200. [Abstract]

    Customer Validation
     Ac4ManNAz (50 μM; 72 h). qRT-PCR analysis comparing the relative expression level of IL-1β between M1 macrophages and Ac4ManNAz-treated M1 macrophages (Ac4/M1).

  • 1/16

    Ac4ManNAz purchased from MedChemExpress. Usage Cited in: Int J Nanomedicine. 2025 Nov 26:20:14185-14200. [Abstract]

    Customer Validation
     Ac4ManNAz (50 μM; 72 h). Fluorescence microscopy imaging of macrophages labeled with DBCO-Cy5 after Ac4ManNAz treatment. Hoechst staining shows nuclei (blue), while DBCO-Cy5 indicates successful surface labeling (red). The merged image highlights specific azide-dependent bioorthogonal chemistry, with scale bars representing 100 µm.

  • 1/16

    Ac4ManNAz purchased from MedChemExpress. Usage Cited in: Int J Nanomedicine. 2025 Nov 26:20:14185-14200. [Abstract]

    Customer Validation
     Ac4ManNAz (50 μM; 72 h). Morphological comparison of M0, M1, and Ac4ManNAz-treated M1 macrophages.

  • 1/16

    Ac4ManNAz purchased from MedChemExpress. Usage Cited in: Int J Nanomedicine. 2025 Nov 26:20:14185-14200. [Abstract]

    Customer Validation
     Ac4ManNAz (50 μM; 72 h). qRT-PCR results showing that with Ac4ManNAz-treated M1EV (Ac4M1EV) significantly upregulated M1 macrophage markers IL-1β and CXCL10, while downregulating the M2 macrophage marker CD206 compared with M0 macrophages.

  • Ac4ManNAz