AM4299 A
AM4299 A is a thiol protease inhibitor with IC50 values of 73, 390 and 88 nM against Cathepsin B, Cathepsin L and Papain, respectively. AM4299 A shows low toxicity and favorable biosafety in mice. AM4299 A can be used in studies related to osteoporosis and parasitic diseases.
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- No. CAS: 160825-48-9
- Fòrmula: C15H26N2O6
- Peso molecular:330.38
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Almacenamiento:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Ver todos los productos específicos de isoformas Cathepsin
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Actividad biológica
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Cathepsin C 73 nM (IC50) |
cathepsin L 390 nM (IC50) |
papain 88 nM (IC50) |
AM4299 A specifically inhibits purified bovine spleen cathepsin B (IC50 = 7.3 × 10-8 M), human kidney cathepsin L (IC50 = 3.9 × 10-7 M), and Carica papaya papain (IC50 = 8.8 × 10-8 M), with no activity against bovine pancreas trypsin or α-chymotrypsin at concentrations up to 8.0 × 10-5 M[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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No. CAS 160825-48-9
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Peso molecular 330.38
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Fòrmula C15H26N2O6
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SMILES
C(N[C@H](C(NCCCCCO)=O)CC(C)C)(=O)C1C(C(O)=O)O1
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Envío
Room temperature in continental US; may vary elsewhere.
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Almacenamiento
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureza y Documentación
Referencias
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
AM4299 A Related Classifications
HY-187615 Related Classifications
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