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Referencia número: HY-186015

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Arg-TERRα

Arg-TERRα is a mini-PROTAC targeting ERRα. Arg-TERRα induces ERRα degradation via the N-end rule pathway, thereby in inhibiting the proliferation and migration of MCF7 breast cancer cells. Arg-TERRα can be used for breast cancer research.
(Pink: ERRα Target protein ligand; Blue: Ligands for E3 Ligase ligand (HY-N0455); Black: linker).

Para uso exclusivo en investigación. No vendemos a pacientes.

No. CAS: 2408832-28-8
Fòrmula: C₃₁H₃₃F₃N₁₀O₅S
Peso molecular:714.72

Almacenamiento:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (263 KB)

Arg-TERRα Chemical Structure

No. CAS: 2408832-28-8

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Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Actividad biológica

Descripciòn

Arg-TERRα is a mini-PROTAC targeting ERRα. Arg-TERRα induces ERRα degradation via the N-end rule pathway, thereby in inhibiting the proliferation and migration of MCF7 breast cancer cells. Arg-TERRα can be used for breast cancer research^[1]. (Pink: ERRα Target protein ligand; Blue: Ligands for E3 Ligase ligand (HY-N0455); Black: linker).

Ver todos los productos específicos de isoformas PROTACs :

Ver todos los productos específicos de isoformas Estrogen Receptor/ERR :

Chemical Information

No. CAS 2408832-28-8
Peso molecular 714.72
Fòrmula C₃₁H₃₃F₃N₁₀O₅S
SMILES

FC(F)(F)C(C=C(C=C1)C#N)=C1OC2=C(C=C(C=C2)/C=C3C(N(C(S\3)=O)CC4=CN(N=N4)CCCNC([C@@H](N)CCCNC(N)=N)=O)=O)OC
Envío

Room temperature in continental US; may vary elsewhere.
Almacenamiento

Please store the product under the recommended conditions in the Certificate of Analysis.

Pureza y Documentación

Select Batch:

Pureza: 99.98%

Assay: 99.98%

ee.: 99.98%

Ficha de datos (263 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Instrucciones de manejo (2659 KB)

Referencias

[1]. Chen X, et al. Mighty mini-PROTACs: an emerging class of degraders. Eur J Med Chem. 2026 Jan 5;301:118202. [Content Brief]

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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Arg-TERRα

Ver todos los productos específicos de isoformas PROTACs

Ver todos los productos específicos de isoformas Estrogen Receptor/ERR

Actividad biológica

Chemical Information

Pureza y Documentación

Referencias

Calculators

Help & FAQs

Arg-TERRα Related Classifications

HY-186015 Related Classifications