AZ5385
AZ5385 is an EGFR-tyrosine kinase inhibitor. AZ5385 is a HRV-2 virus blocker, with EC50 of 0.35 µM. AZ5385 affects the late stage of viral life cycle.
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- No. CAS: 848439-89-4
- Fòrmula: C22H22ClFN4O4
- Peso molecular:460.89
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Almacenamiento:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Actividad biológica
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Chemical Information
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Actividad biológica
AZ5385 (72 h) shows a CC50 of 9 µM for HeLa cells[1].
AZ5385 (3 h prior to the addition ofvirus, following incubation at 37°C for 72 h) also inhibits infection of HEp-2 cellscells by HRV-16, and RSV strain A2, with EC50s of 3.6 and 0.4 µM [1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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No. CAS 848439-89-4
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Peso molecular 460.89
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Fòrmula C22H22ClFN4O4
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SMILES
C[C@H](O)C(N(CC1)CCC1OC(C(O)=C2)=CC3=C2C(NC4=C(C(Cl)=CC=C4)F)=NC=N3)=O
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Envío
Room temperature in continental US; may vary elsewhere.
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Almacenamiento
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureza y Documentación
Referencias
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
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