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Bexmarilimab

(Synonyms: FP-1305)
1 Cited Publications
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Based on 1 publication(s) in Google Scholar

Bexmarilimab (FP-1305) is a potent humanized anti-CLEVER-1 IgG4 antibody with an IC50 value of 4.51 nM. Bexmarilimab is capable of inducing a phenotypic M2 to M1 immune switch of tumor-associated macrophages. Bexmarilimab can promote antigen presentation and pro-inflammatory cytokine secretion. Bexmarilimab can induce B-cell and T-cell activation. Bexmarilimab can be used in researches of immunology and cancer, such as colorectal carcinoma.

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  • Pureza: 95.00%
  • No. CAS: 2259301-27-2
  • Peso molecular:146.22 kDa
  • Almacenamiento:

    Please store the product under the recommended conditions in the Certificate of Analysis.

  • Experimental Validation Results for Bexmarilimab
  • Experimental Validation Results for Bexmarilimab
  • Bexmarilimab Chemical Structure
    Bexmarilimab Chemical Structure
No. CAS: 2259301-27-2
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609-228-6898
[email protected] [email protected]
Encuentre su distribuidor local Your local distributor: Hycultec GmbHHycultec
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Assay Types
  • 1/16

    Human IgG4 kappa

  • 1/16

    Flow cytometric analysis of 1X106 MCF-7 cells with Bexmarilimab (HY-P99320, red). Cells were fixed with 4% paraformaldehyde. Then stained with the primary antibody at 1/200 dilution for an hour at 4℃. Alexa Fluor 488-conjugated AffiniPure Goat Anti-Human IgG H&L (AF488) (HY-P83776) was used as the secondary antibody at 1/1,000 dilution for 30 minutes at 4℃. Human IgG4 kappa (HY-P99003, blue) was used as the isotype control, cells without incubation with primary antibody were used as the unlabeled control (black).

  • Bexmarilimab Chemical Structure
    1/16
  • Bexmarilimab
  • Flow cytometric analysis of 1X106 MCF-7 cells with Bexmarilimab (HY-P99320, red). Cells were fixed with 4% paraformaldehyde. Then stained with the primary antibody at 1/200 dilution for an hour at 4℃. Alexa Fluor 488-conjugated AffiniPure Goat Anti-Human IgG H&L (AF488) (HY-P83776) was used as the secondary antibody at 1/1,000 dilution for 30 minutes at 4℃. Human IgG4 kappa (HY-P99003, blue) was used as the isotype control, cells without incubation with primary antibody were used as the unlabeled control (black).