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Referencia número: HY-N10575

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Bornesitol

Bornesitol is a natural cytotoxic agent found in Michelia compressa var. lanyuensis. Bornesitol exhibits cytotoxic and antiproliferative activities, and can be used in melanoma research.

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No. CAS: 484-71-9
Fòrmula: C₇H₁₄O₆
Peso molecular:194.18

Almacenamiento:

Please store the product under the recommended conditions in the Certificate of Analysis.

Bornesitol Chemical Structure

No. CAS: 484-71-9

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Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Actividad biológica
- Descripciòn
- In Vitro
Chemical Information
Pureza y Documentación
Referencias
Calculators
Help & FAQs
Classifications
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Actividad biológica

Descripciòn

Bornesitol is a natural cytotoxic agent found in Michelia compressa var. lanyuensis. Bornesitol exhibits cytotoxic and antiproliferative activities, and can be used in melanoma research^[1].

In Vitro

Anti-cancerOthers

Anti-cancer

Bornesitol (1-100 μM; 24 h) shows no cytotoxicity against B16F10 melanoma cells at concentrations of 1 μM or 10 μM after 24 h of incubation, but induces cytotoxicity at a concentration of 100 μM^[1].

Others

Bornesitol (5 μM; 48 h) exerts only an extremely weak inhibitory effect on melanin content in B16F10 melanoma cells, with an inhibition rate of 0.89% after 48 h of incubation^[1].
Bornesitol (5 μM; 48 h) weakly inhibits tyrosinase activity in B16F10 melanoma cells after incubation at 5 μM for 48 h, with an inhibition rate of 3.06%^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Cell Viability Assay^[1]

Cell Line:

B16F10 melanoma cells
Concentration:

1 μM; 10 μM; 100 μM
Incubation Time:

24 h
Result:

Did not reduce B16F10 cell viability relative to vehicle control at 1 μM and 10 μM.
Caused cytotoxicity, reducing cell viability relative to vehicle control at 100 μM.

Related Protocols :

Cell Viability Determination by MTT Colorimetric Assay

Chemical Information

No. CAS 484-71-9
Peso molecular 194.18
Fòrmula C₇H₁₄O₆
SMILES

O(C)[C@H]1[C@H](O)[C@@H](O)[C@H](O)[C@@H](O)[C@H]1O
Structure Classification
- Others
Initial Source
Envío

Room temperature in continental US; may vary elsewhere.
Almacenamiento

Please store the product under the recommended conditions in the Certificate of Analysis.

Pureza y Documentación

Instrucciones de manejo (2659 KB)

Referencias

[1]. Chu CW, et al. Biofunctional Constituents from Michelia compressa var. lanyuensis with Anti-Melanogenic Properties. Molecules (Basel, Switzerland). 2015 Jul 03;20(7):12166-74. [Content Brief]

Calculators

Calculadora de molaridad

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Calculadora de dilución

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

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Concentration _(final) Concentration _(final)

Volume _(final) Volume _(final)

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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