CAY10535
CAY10535 is a FP and TP receptor inhibitor and can be used for research of cardiovascular diseases.
Para uso exclusivo en investigación. No vendemos a pacientes.
- No. CAS: 945716-28-9
- Fòrmula: C18H21N3O7S
- Peso molecular:423.44
-
Almacenamiento:
Please store the product under the recommended conditions in the Certificate of Analysis.
Actividad biológica
Descripciòn
IC50 & Target
|
TP Receptor |
FP Receptor |
Cellular Effect
|
Cell Line
|
Type | Value | Description | References |
|---|---|---|---|---|
| HEK293 | IC50 |
1970 nM
Compound: 9ag
|
Antagonist activity at human thromboxane A2 receptor isoform alpha expressed in HEK293 cells assessed as inhibition of U46619-induced calcium mobilization
Antagonist activity at human thromboxane A2 receptor isoform alpha expressed in HEK293 cells assessed as inhibition of U46619-induced calcium mobilization
|
[PMID: 17630727] |
| HEK293 | IC50 |
99 nM
Compound: 9ag
|
Antagonist activity at human thromboxane A2 receptor isoform beta expressed in HEK293 cells assessed as inhibition of U46619-induced calcium mobilization
Antagonist activity at human thromboxane A2 receptor isoform beta expressed in HEK293 cells assessed as inhibition of U46619-induced calcium mobilization
|
[PMID: 17630727] |
In Vitro
CAY10535 (10 μM) significantly inhibits PGF2α (1 μM) and/or capsaicin (2 μM) induced coronary rings contractions[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
-
No. CAS 945716-28-9
-
Peso molecular 423.44
-
Fòrmula C18H21N3O7S
-
SMILES
O=S(C1=CC([N+]([O-])=O)=CC=C1OC2=CC=CC(OC)=C2)(NC(NC(C)(C)C)=O)=O
-
Envío
Room temperature in continental US; may vary elsewhere.
-
Almacenamiento
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureza y Documentación
Referencias
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)