CEE321
Based on 1 Customer Validation
CEE321 is a potent pan-JAK inhibitor with an IC50 value of 54 nM. CEE321 potently inhibits biomarkers associated with atopic dermatitis.
Para uso exclusivo en investigación. No vendemos a pacientes.
- Pureza : 98.74%
- No. CAS: 2098545-89-0
- Fòrmula: C18H16ClN5O
- Peso molecular:353.81
-
Almacenamiento:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
-
Actividad biológica
-
Chemical Information
-
Solvente y solubilidad
- Protocolo
- Pureza y Documentación
- Referencias
-
Help & FAQs
Actividad biológica
Descripciòn
Ensayo clínico
| NCT Number | Sponsor | Condition | Start Date |
Phase
|
|---|---|---|---|---|
| NCT01329991 | 2011-05 | PHASE1 |
Chemical Information
-
No. CAS 2098545-89-0
-
Appearance Solid
-
Peso molecular 353.81
-
Fòrmula C18H16ClN5O
-
Color Off-white to light yellow
-
SMILES
O=C(C1=CN=C(NC2=CC=CC(C)=N2)C=C1NC3=C(Cl)C=CC=C3)N
-
Envío
Room temperature in continental US; may vary elsewhere.
-
Almacenamiento
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Solvente y solubilidad
In Vitro:
DMSO : 100 mg/mL (282.64 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Pureza y Documentación
-
Ficha de datos (270 KB)
-
SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
-
Instrucciones de manejo (2659 KB)
Referencias
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 2.8264 mL | 14.1319 mL | 28.2638 mL | 70.6594 mL |
| 5 mM | 0.5653 mL | 2.8264 mL | 5.6528 mL | 14.1319 mL | |
| 10 mM | 0.2826 mL | 1.4132 mL | 2.8264 mL | 7.0659 mL | |
| 15 mM | 0.1884 mL | 0.9421 mL | 1.8843 mL | 4.7106 mL | |
| 20 mM | 0.1413 mL | 0.7066 mL | 1.4132 mL | 3.5330 mL | |
| 25 mM | 0.1131 mL | 0.5653 mL | 1.1306 mL | 2.8264 mL | |
| 30 mM | 0.0942 mL | 0.4711 mL | 0.9421 mL | 2.3553 mL | |
| 40 mM | 0.0707 mL | 0.3533 mL | 0.7066 mL | 1.7665 mL | |
| 50 mM | 0.0565 mL | 0.2826 mL | 0.5653 mL | 1.4132 mL | |
| 60 mM | 0.0471 mL | 0.2355 mL | 0.4711 mL | 1.1777 mL | |
| 80 mM | 0.0353 mL | 0.1766 mL | 0.3533 mL | 0.8832 mL | |
| 100 mM | 0.0283 mL | 0.1413 mL | 0.2826 mL | 0.7066 mL |
CEE321 Related Classifications
HY-169758 Related Classifications
Powered by Bioz