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G15

42 Cited Publications
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Based on 42 publication(s) in Google Scholar

G15 is a high affinity and selective G-protein-coupled estrogen receptor (GPER/GPR30) antagonist with a Ki of 20 nM.

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  • Pureza: 99.0%
  • No. CAS: 1161002-05-6
  • Fòrmula: C19H16BrNO2
  • Peso molecular:370.24
  • Almacenamiento:

    -20°C, protect from light

    * In solvent : -80°C, 2 years; -20°C, 1 year (protect from light)

  • G15 Chemical Structure
    G15 Chemical Structure
  • Experimental Validation Results for G15
  • Experimental Validation Results for G15
  • Experimental Validation Results for G15
  • Experimental Validation Results for G15
  • Experimental Validation Results for G15
No. CAS: 1161002-05-6
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Encuentre su distribuidor local Your local distributor: Hycultec GmbHHycultec
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  • G15 Chemical Structure
    G15 Chemical Structure
    1/16
  • 1/16

    G15 purchased from MedChemExpress. Usage Cited in: Poult Sci. 2025 Dec 5;105(1):106210. [Abstract]

    Customer Validation
     Effects of selective receptor agonists (PPT, DPN and G-1) treatment (3 h) on PGR expression, and antagonist (ICI and G15) treatment (3 h) on E2-upregulated PGR expression, in cultured pituitary cells from female chicks.

  • 1/16

    G15 purchased from MedChemExpress. Usage Cited in: Pharm Biol. 2023 Dec;61(1):499-513. [Abstract]

    Customer Validation
     TMYX enhanced the dilation function of coronary microvessels in vitro, but this effect was inhibited by G-15.

  • 1/16

    G15 purchased from MedChemExpress. Usage Cited in: Cell Death Dis. 2022 Apr 19;13(4):372. [Abstract]

    Customer Validation
     J774A.1 cells were pre-treated with DHEA (50 μM) in the presence or absence of the GPER inhibitor G15 (1 μM) for 1 h, then stimulated with LPS for 4 h. The TLR4, p-ERK/ERK, LC3, p62, p-mTOR, and p-AMPK protein expression levels were measured by western blotting and quantified by Image J software.

  • 1/16

    G15 purchased from MedChemExpress. Usage Cited in: Cell Death Dis. 2022 Apr 19;13(4):372. [Abstract]

    Customer Validation
     J774A.1 cells were pre-treated with G1 (1 μM) for 1 h, then stimulated with LPS for 4 h, and the indicated protein expression levels were measured by western blotting and quantified by Image J software.

  • 1/16

    G15 purchased from MedChemExpress. Usage Cited in: Cell Death Dis. 2022 Apr 19;13(4):372. [Abstract]

    Customer Validation
     J774A.1 cells were pre-treated with DHEA (50 μM) in the presence or absence of the GPER inhibitor G15 (1 μM) for 1 h, then stimulated with LPS for 4 h, PI-positive dead cells in 5 randomly selected fluorescence microscope images were counted by Image J software, scale bar = 200 μm.

  • G15