Hypericin-d2
Based on 1 Customer Validation
Hypericin-d2 is deuterium labeled Hypericin.
Para uso exclusivo en investigación. No vendemos a pacientes.
- Pureza: 94.68%
- Fòrmula: C30H14D2O8
- Peso molecular:506.46
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Almacenamiento:Powder -20°C, 3 years ; In solvent -80°C, 6 months , -20°C, 1 month
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Actividad biológica
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Chemical Information
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Solvente y solubilidad
- Pureza y Documentación
- Referencias
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Help & FAQs
Actividad biológica
Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
1. This compound can be used as a tracer
2. This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
Chemical Information
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Unlabeled Cas 548-04-9
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Appearance Solid
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Peso molecular 506.46
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Fòrmula C30H14D2O8
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Color Light brown to brown
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SMILES
O=C1C2=C(O)C([2H])=C(O)C3=C2C4=C(C5=C6C(O)=CC(C)=C5C7=C4C1=C(O)C=C7C)C8=C3C(O)=C([2H])C(O)=C8C6=O
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Envío
Room temperature in continental US; may vary elsewhere.
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Almacenamiento
Powder -20°C 3 years In solvent -80°C 6 months -20°C 1 month
Solvente y solubilidad
DMSO : 250 mg/mL (493.62 mM; ultrasonic and warming and heat to 60°C; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Pureza y Documentación
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Ficha de datos (284 KB)
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SDS (251 KB)
- English - EN (251 KB)
- Français - FR (251 KB)
- Deutsch - DE (251 KB)
- Norwegian - NO (251 KB)
- Español - ES (251 KB)
- Swedish - SV (251 KB)
- Italian - IT (251 KB)
- Korean - KR (251 KB)
- Portuguese - PT (251 KB)
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Instrucciones de manejo (2659 KB)
Referencias
[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216. [Content Brief]
[2]. Agostinis P et al. Hypericin in cancer treatment: more light on the way. Int J Biochem Cell Biol. 2002 Mar;34(3):221-41. [Content Brief]
[3]. Lenard J et al. Photodynamic inactivation of infectivity of human immunodeficiency virus and other enveloped viruses usinghypericin and rose bengal: inhibition of fusion and syncytia formation. Proc Natl Acad Sci U S A. 1993 Jan 1;90(1):158-62. [Content Brief]
[4]. Hwang MS et al. Inhibition of c-erbB-2 expression an activity in human ovarian carcinoma cells by hypericin. Anticancer Res. 2001 Jul-Aug;21(4A):2649-55. [Content Brief]
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 1.9745 mL | 9.8724 mL | 19.7449 mL | 49.3622 mL |
| 5 mM | 0.3949 mL | 1.9745 mL | 3.9490 mL | 9.8724 mL | |
| 10 mM | 0.1974 mL | 0.9872 mL | 1.9745 mL | 4.9362 mL | |
| 15 mM | 0.1316 mL | 0.6582 mL | 1.3163 mL | 3.2908 mL | |
| 20 mM | 0.0987 mL | 0.4936 mL | 0.9872 mL | 2.4681 mL | |
| 25 mM | 0.0790 mL | 0.3949 mL | 0.7898 mL | 1.9745 mL | |
| 30 mM | 0.0658 mL | 0.3291 mL | 0.6582 mL | 1.6454 mL | |
| 40 mM | 0.0494 mL | 0.2468 mL | 0.4936 mL | 1.2341 mL | |
| 50 mM | 0.0395 mL | 0.1974 mL | 0.3949 mL | 0.9872 mL | |
| 60 mM | 0.0329 mL | 0.1645 mL | 0.3291 mL | 0.8227 mL | |
| 80 mM | 0.0247 mL | 0.1234 mL | 0.2468 mL | 0.6170 mL | |
| 100 mM | 0.0197 mL | 0.0987 mL | 0.1974 mL | 0.4936 mL |
Hypericin-d2 Related Classifications
HY-N0453S1 Related Classifications
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