IPS-06061
IPS-06061 is an orally active molecular glue forming a ternary complex of CRBN-KRASG12D-IPS06061, degrading KRASG12D with a DC50 value lower than 500 nM. IPS-06061 shows a strong anti-tumor efficacy.
Para uso exclusivo en investigación. No vendemos a pacientes.
- No. CAS: 3064065-83-1
- Fòrmula: C21H25NO3
- Peso molecular:339.43
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Almacenamiento:
Please store the product under the recommended conditions in the Certificate of Analysis.
Actividad biológica
Descripciòn
IC50 & Target
[2]|
KRas G12D <500 nM (DC50) |
Cereblon |
In Vivo
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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No. CAS 3064065-83-1
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Peso molecular 339.43
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Fòrmula C21H25NO3
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SMILES
O=C(OCC)[C@@H](N[C@H](C(C1=CC=CC=C1)=O)C)CCC2=CC=CC=C2
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Envío
Room temperature in continental US; may vary elsewhere.
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Almacenamiento
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureza y Documentación
Referencias
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)