JJO-1
JJO-1 is an AMPK activator with an EC50 of 1.8 μM. JJO-1 can be used in the study of obesity and type 2 diabetes.
Para uso exclusivo en investigación. No vendemos a pacientes.
- No. CAS: 16722-44-4
- Fòrmula: C19H13N3
- Peso molecular:283.33
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Almacenamiento:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Actividad biológica
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| COS-7 | EC50 |
1.8 μM
Compound: 29
|
Activation of human recombinant AMPK GST-tagged alpha1/Myc-tagged beta1/HA-tagged gamma1 expressed in African green monkey COS7 cells assessed as increase in SAMS peptide phosphorylation measured after 10 mins in presence of [gamma33P]ATP by scintillation
Activation of human recombinant AMPK GST-tagged alpha1/Myc-tagged beta1/HA-tagged gamma1 expressed in African green monkey COS7 cells assessed as increase in SAMS peptide phosphorylation measured after 10 mins in presence of [gamma33P]ATP by scintillation
|
[PMID: 27727125] |
Chemical Information
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No. CAS 16722-44-4
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Peso molecular 283.33
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Fòrmula C19H13N3
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SMILES
C1(/C=N/C2=CN=C3C=CC=CC3=C2)=CC=C4C=CC=CC4=N1
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Envío
Room temperature in continental US; may vary elsewhere.
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Almacenamiento
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureza y Documentación
Referencias
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)