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Referencia número: HY-105479

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KF 18259

KF 18259 is a 5-HT3-receptor antagonist. KF 18259 inhibits the wrap-restraint stress-induced propulsive motility of the proximal and distal colon.

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No. CAS: 139094-48-7
Fòrmula: C₂₂H₂₉ClN₂O₃
Peso molecular:404.93

Almacenamiento:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (273 KB)

KF 18259 Chemical Structure

No. CAS: 139094-48-7

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Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

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Descripciòn

KF 18259 is a 5-HT3-receptor antagonist. KF 18259 inhibits the wrap-restraint stress-induced propulsive motility of the proximal and distal colon^[1].

IC₅₀ & Target^[1]

5-HT₃ Receptor

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Chemical Information

No. CAS 139094-48-7
Peso molecular 404.93
Fòrmula C₂₂H₂₉ClN₂O₃
SMILES

CN([C@@H](CC1)C2)[C@H]1C[C@@H]2OC(C(C3=CC=CC=C3N4CC(C)C)=CC4=O)=O.Cl
Envío

Room temperature in continental US; may vary elsewhere.
Almacenamiento

Please store the product under the recommended conditions in the Certificate of Analysis.

Pureza y Documentación

Select Batch:

Pureza: 99.98%

Assay: 99.98%

ee.: 99.98%

Ficha de datos (273 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Instrucciones de manejo (2659 KB)

Referencias

[1]. Kishibayashi N, et al. Pharmacological properties of KF18259, a novel 5-HT3-receptor antagonist, in rats: inhibition of the distal colonic function. Jpn J Pharmacol. 1993 Dec;63(4):495-502. [Content Brief]

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How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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KF 18259

Ver todos los productos específicos de isoformas 5-HT Receptor

Actividad biológica

Chemical Information

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Referencias

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KF 18259 Related Classifications

HY-105479 Related Classifications