Lilotomab
Based on 1 Customer Validation
Lilotomab (HH1) is a murine anti-CD37 monoclonal antibody. Lilotomab reduces clonogenic survival. Lilotomab shows anti-tumor activity.
Para uso exclusivo en investigación. No vendemos a pacientes.
- Pureza : 98.99%
- No. CAS: 1453362-55-4
- Peso molecular:145.24 kDa
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Almacenamiento:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Actividad biológica
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Chemical Information
- Pureza y Documentación
- Referencias
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Help & FAQs
Actividad biológica
Descripciòn
Isotype
Human IgG1 kappa
Recommend Isotype Controls
Species Reactivity
Human
IC50 & Target
TSPAN26/CD37
In Vitro
Lilotomab (0-40 µg/mL; 12 days) reduces the clonogenic survival of DOHH2 and Ramos cells[1].
Lilotomab (40 µg/mL; 18 h) induces slight apoptosis in DOHH2 cells[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
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Cell Line:Ramos, DOHH2, Rec-1 cells
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Concentration:40 µg/mL
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Incubation Time:18 h
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Result:Induced apoptosis in DOHH2 cells.
In Vivo
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
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Animal Model:SCID mice (DOHH2 cell xenografts)[1]
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Dosage:0.5 mg/kg
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Administration:I.v.; once
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Result:Inhibited tumor growth and increased mouse survival.
Ensayo clínico
| NCT Number | Sponsor | Condition | Start Date |
Phase
|
|---|---|---|---|---|
| NCT01329991 | Plexxikon| | 2011-05 | PHASE1 |
Gene ID
Accession
Conjugated
Unconjugated
Reconsititution
The product can be reconstituted/diluted with sterile PBS or saline.
Format
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IgG1-kappa
Aplicación
ELISA, FACS, Functional assay
Verified Bioactivity
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Flow Cytometry analysis of Raji cells labelling TSPAN26/CD37 (red) with Lilotomab (anti-TSPAN26/CD37) (HY-P99707). Goat Anti-Human IgG (Alexa Fluor 488) (HY-P83776) at a dilution of 1/1000 was used as the secondary antibody. Blue-Human IgG1 kappa (HY-P99001). Black-Unlabelled control, cells without incubation with primary antibody.
Chemical Information
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No. CAS 1453362-55-4
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Appearance Liquid
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Peso molecular 145.24 kDa
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Color Colorless to light yellow
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SMILES
[Lilotomab]
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Synonyms
HH1
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Envío
Shipping with dry ice.
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Formulation
Please refer to the lot-specific COA for specific buffer information.
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Almacenamiento
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureza y Documentación
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Ficha de datos (259 KB)
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SDS (251 KB)
- English - EN (251 KB)
- Français - FR (251 KB)
- Deutsch - DE (251 KB)
- Norwegian - NO (251 KB)
- Español - ES (251 KB)
- Swedish - SV (251 KB)
- Italian - IT (251 KB)
- Korean - KR (251 KB)
- Portuguese - PT (251 KB)
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Inhibitory Antibodies User Guide (603 KB)
Referencias
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Lilotomab Related Classifications
HY-P99707 Related Classifications
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