Menoxymycin A
Menoxymycin A is an antibiotic. Menoxymycin A has a cytotoxic effect. Menoxymycin A inhibits KB and N18-RE-105 cells with IC50s of 0.86 μM and 0.14 μM.
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- No. CAS: 160492-65-9
- Fòrmula: C24H27NO9
- Peso molecular:473.47
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Almacenamiento:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Actividad biológica
Descripciòn
Chemical Information
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No. CAS 160492-65-9
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Peso molecular 473.47
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Fòrmula C24H27NO9
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SMILES
O=C1C2=C([C@H](O[C@@]3([H])[C@]2([H])OC(C3)=O)C)C(C4=C(O)C([C@H]5C[C@H]([C@@H]([C@H](O5)C)O)N(C)(C)=O)=CC=C41)=O
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Structure Classification
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Initial Source
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Envío
Room temperature in continental US; may vary elsewhere.
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Almacenamiento
Please store the product under the recommended conditions in the Certificate of Analysis.
Protocolo
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Cell Viability Determination by MTT Colorimetric Assay
The following protocol uses the MTT colorimetric assay as a classic literature-established method for assessing cell viability/metabolic activity in cultured mammalian cells. MTT[3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide] is reduced by metabolically active cells to a colored formazan product; the amount of formazan is quantified spectrophotometrically and provides an indirect measure of metabolically active viable cells. Importantly, MTT reduction reflects cellular oxidoreductase/metabolic activity rather than an absolute direct count of living cells, so changes in cellular metabolism can alter the signal independently of cell number.
Pureza y Documentación
Referencias
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)