MM-206
Based on 1 Customer Validation
MM-206, a STAT3 activity inhibitor, potently inhibits the STAT3 SH2 domain-phosphopeptide interaction with IC50 of 1.2 μM. MM-206 demonstrates dose-dependent induction of apoptosis in acute myeloid leukemia (AML) cell lines.
Para uso exclusivo en investigación. No vendemos a pacientes.
- Pureza : 99.9%
- No. CAS: 1809581-87-0
- Fòrmula: C22H12F5NO3S2
- Peso molecular:497.46
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Almacenamiento:Powder -20°C, 3 years ; In solvent -80°C, 6 months , -20°C, 1 month
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Actividad biológica
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Chemical Information
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Solvente y solubilidad
- Pureza y Documentación
- Referencias
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Help & FAQs
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Actividad biológica
Descripciòn
Chemical Information
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No. CAS 1809581-87-0
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Appearance Solid
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Peso molecular 497.46
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Fòrmula C22H12F5NO3S2
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Color Off-white to light yellow
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SMILES
O=S(C1=C(C(F)=C(C(F)=C1F)F)F)(NC2=C3C=CC=CC3=C(C(SC4=CC=CC=C4)=C2)O)=O
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Envío
Room temperature in continental US; may vary elsewhere.
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Almacenamiento
Powder -20°C 3 years In solvent -80°C 6 months -20°C 1 month
Solvente y solubilidad
In Vitro:
DMF : 25 mg/mL (50.26 mM; Need ultrasonic and warming)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Pureza y Documentación
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Ficha de datos (275 KB)
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SDS (251 KB)
- English - EN (251 KB)
- Français - FR (251 KB)
- Deutsch - DE (251 KB)
- Norwegian - NO (251 KB)
- Español - ES (251 KB)
- Swedish - SV (251 KB)
- Italian - IT (251 KB)
- Korean - KR (251 KB)
- Portuguese - PT (251 KB)
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Instrucciones de manejo (2659 KB)
Referencias
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMF | 1 mM | 2.0102 mL | 10.0511 mL | 20.1021 mL | 50.2553 mL |
| 5 mM | 0.4020 mL | 2.0102 mL | 4.0204 mL | 10.0511 mL | |
| 10 mM | 0.2010 mL | 1.0051 mL | 2.0102 mL | 5.0255 mL | |
| 15 mM | 0.1340 mL | 0.6701 mL | 1.3401 mL | 3.3504 mL | |
| 20 mM | 0.1005 mL | 0.5026 mL | 1.0051 mL | 2.5128 mL | |
| 25 mM | 0.0804 mL | 0.4020 mL | 0.8041 mL | 2.0102 mL | |
| 30 mM | 0.0670 mL | 0.3350 mL | 0.6701 mL | 1.6752 mL | |
| 40 mM | 0.0503 mL | 0.2513 mL | 0.5026 mL | 1.2564 mL | |
| 50 mM | 0.0402 mL | 0.2010 mL | 0.4020 mL | 1.0051 mL |
MM-206 Related Classifications
HY-121725 Related Classifications
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