NC1153
NC1153 is a Mannich base with the activity to block IL-2-induced JAK3 activation and its downstream substrate STAT5a/b. NC1153 effectively prolongs the survival of kidney transplants in MHC/non-MHC mismatched rats. NC1153 promotes long-term graft survival and includes multiple toxicity protection for recipients. NC1153 combined with cyclosporine A (CsA) can synergistically prolong graft survival without producing nephrotoxicity, myelotoxicity or lipotoxicity.
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- No. CAS: 150661-91-9
- Fòrmula: C18H38Cl2N2O
- Peso molecular:369.41
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Almacenamiento:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Actividad biológica
Chemical Information
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No. CAS 150661-91-9
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Peso molecular 369.41
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Fòrmula C18H38Cl2N2O
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SMILES
O=C1C(CN(C)C)CCCCCCCCCC1CN(C)C.Cl.Cl
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Envío
Room temperature in continental US; may vary elsewhere.
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Almacenamiento
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureza y Documentación
Referencias
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
NC1153 Related Classifications
HY-115464 Related Classifications
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