P7–2302
P7-2302 inhibits PDE7 and PDE4B with IC50 of 0.18 nM and 77.3 nM. P7-2302 inhibits the efflux of P-gp and BCRP (breast cancer resistance protein), exhibits low uptake in rats brain. P7-2302 can be used as a PET tracer when labeled with 18F.
Para uso exclusivo en investigación. No vendemos a pacientes.
- Fòrmula: C23H21ClF2N2O4
- Peso molecular:462.87
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Almacenamiento:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Actividad biológica
Descripciòn
IC50 & Target
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PDE7 0.18 nM (IC50) |
PDE4B 77.3 nM (IC50) |
Chemical Information
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Peso molecular 462.87
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Fòrmula C23H21ClF2N2O4
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SMILES
O=C(N1CC(F)C1)C2=C(OC3=C4C(NC(OC45CCCCC5)=O)=C(Cl)C=C3)C(F)=CC=C2
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Envío
Room temperature in continental US; may vary elsewhere.
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Almacenamiento
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureza y Documentación
Referencias
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
P7–2302 Related Classifications
HY-172365 Related Classifications
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